Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   Q3101_RS07415 Genome accession   NZ_CP133215
Coordinates   1575076..1575717 (-) Length   213 a.a.
NCBI ID   WP_064727172.1    Uniprot ID   A0A191UVS1
Organism   Streptomyces sp. VNUA74     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1570076..1580717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q3101_RS07385 (Q3101_07385) - 1570501..1571007 (+) 507 WP_064727166.1 HNH endonuclease -
  Q3101_RS07390 (Q3101_07390) - 1571221..1572165 (-) 945 WP_064727167.1 SPFH domain-containing protein -
  Q3101_RS07395 (Q3101_07395) - 1572308..1572739 (-) 432 WP_064727168.1 NfeD family protein -
  Q3101_RS07400 (Q3101_07400) - 1572794..1573591 (-) 798 WP_064727169.1 ABC transporter ATP-binding protein -
  Q3101_RS07405 (Q3101_07405) - 1573743..1574525 (+) 783 WP_064727170.1 hypothetical protein -
  Q3101_RS07410 (Q3101_07410) chpE 1574695..1574940 (-) 246 WP_161345916.1 chaplin ChpE -
  Q3101_RS07415 (Q3101_07415) vraR 1575076..1575717 (-) 642 WP_064727172.1 response regulator transcription factor Regulator
  Q3101_RS07420 (Q3101_07420) - 1575710..1576888 (-) 1179 WP_064727173.1 GAF domain-containing sensor histidine kinase -
  Q3101_RS07425 (Q3101_07425) - 1577110..1577808 (+) 699 WP_283015198.1 SDR family oxidoreductase -
  Q3101_RS07430 (Q3101_07430) - 1577805..1578848 (+) 1044 WP_161345920.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  Q3101_RS07435 (Q3101_07435) - 1579201..1579902 (+) 702 WP_064727176.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22951.19 Da        Isoelectric Point: 5.3486

>NTDB_id=798735 Q3101_RS07415 WP_064727172.1 1575076..1575717(-) (vraR) [Streptomyces sp. VNUA74]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIVVVGEAADGAEGVDRAQELGPDVILMDVKMPGMDGVDALRRLRELDNHAR
VLVVTSFTEQRTVVPALRAGAAGYVYKDVDPEALAGAIRSVHAGHILLQPEVAGALLSQEEGNSGQGRAGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGLTS

Nucleotide


Download         Length: 642 bp        

>NTDB_id=798735 Q3101_RS07415 WP_064727172.1 1575076..1575717(-) (vraR) [Streptomyces sp. VNUA74]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGATCACCAAGTGGTCCGCCGGGGCCTGCGCACCTTCCTCGAGGTGCA
GGACGACATCGTGGTGGTGGGGGAGGCCGCCGACGGCGCCGAGGGAGTCGACCGCGCCCAGGAACTCGGCCCCGACGTGA
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGCGTCGACGCGCTGCGCAGACTCCGCGAGCTGGACAACCACGCACGC
GTACTGGTCGTCACCAGCTTCACCGAGCAGCGCACCGTCGTCCCGGCCCTGCGCGCGGGCGCGGCGGGCTACGTCTACAA
GGATGTCGACCCCGAGGCGCTGGCCGGCGCCATCCGCTCCGTCCACGCCGGCCACATCCTGCTCCAGCCCGAGGTCGCCG
GCGCCCTGCTCAGCCAGGAGGAGGGCAACTCCGGCCAGGGCCGCGCGGGTTCCCTCACGGAGCGCGAGCGCGAGGTGCTG
GGCCTGATCGCGGACGGGCGCTCCAACCGGGAGATCGCGCGGGCGCTGGTGCTCTCCGAGAAGACCGTCAAGACGCACGT
CTCGAACATCCTCATGAAGCTCGACCTCGCGGACCGCACCCAGGCCGCGCTGTGGGCCGTGCGCCACGGCCTGACCAGCT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A191UVS1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.445

99.061

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

36.199

100

0.376