Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   P1A14_RS00160 Genome accession   NZ_CP119338
Coordinates   41433..43061 (-) Length   542 a.a.
NCBI ID   WP_058332291.1    Uniprot ID   -
Organism   Staphylococcus aureus strain N09HSA11     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 43087..88324 41433..43061 flank 26


Gene organization within MGE regions


Location: 41433..88324
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P1A14_RS00160 (P1A14_00160) ccrB 41433..43061 (-) 1629 WP_058332291.1 recombinase family protein Machinery gene
  P1A14_RS00165 (P1A14_00165) ccrA 43082..44431 (-) 1350 WP_275593721.1 recombinase family protein Machinery gene
  P1A14_RS00170 (P1A14_00170) - 44622..44900 (-) 279 WP_084944755.1 hypothetical protein -
  P1A14_RS00175 (P1A14_00175) - 44970..46769 (-) 1800 WP_275593722.1 DUF927 domain-containing protein -
  P1A14_RS00180 (P1A14_00180) - 46897..48324 (-) 1428 WP_275593723.1 DUF6038 family protein -
  P1A14_RS00185 (P1A14_00185) - 48541..49704 (+) 1164 WP_069854462.1 ATP-binding protein -
  P1A14_RS00190 (P1A14_00190) - 49717..50517 (+) 801 WP_069854463.1 abortive infection family protein -
  P1A14_RS00195 (P1A14_00195) - 51195..51584 (+) 390 WP_049948298.1 DUF6339 family protein -
  P1A14_RS00200 (P1A14_00200) - 51679..51957 (+) 279 WP_224103024.1 DUF2975 domain-containing protein -
  P1A14_RS00205 (P1A14_00205) - 51968..52171 (+) 204 WP_209307420.1 helix-turn-helix transcriptional regulator -
  P1A14_RS00210 (P1A14_00210) - 52520..53623 (+) 1104 WP_053865759.1 DUF418 domain-containing protein -
  P1A14_RS00215 (P1A14_00215) - 53649..54371 (+) 723 WP_031775117.1 CPBP family intramembrane glutamic endopeptidase -
  P1A14_RS00220 (P1A14_00220) - 54571..55665 (+) 1095 WP_031590773.1 IS30 family transposase -
  P1A14_RS00225 (P1A14_00225) - 56474..58075 (+) 1602 Protein_42 L-lactate permease -
  P1A14_RS00230 (P1A14_00230) - 58261..58662 (+) 402 WP_049948297.1 hypothetical protein -
  P1A14_RS00235 (P1A14_00235) - 58826..59209 (-) 384 WP_078098742.1 DDE-type integrase/transposase/recombinase -
  P1A14_RS00240 (P1A14_00240) - 59193..59414 (-) 222 WP_078098741.1 IS3 family transposase -
  P1A14_RS00245 (P1A14_00245) - 59516..59956 (-) 441 WP_031590800.1 HTH domain-containing protein -
  P1A14_RS00250 (P1A14_00250) - 60123..60860 (-) 738 Protein_47 GntR family transcriptional regulator -
  P1A14_RS00255 (P1A14_00255) - 61244..62338 (-) 1095 WP_031590773.1 IS30 family transposase -
  P1A14_RS00260 (P1A14_00260) - 62538..63260 (-) 723 WP_031775117.1 CPBP family intramembrane glutamic endopeptidase -
  P1A14_RS00265 (P1A14_00265) - 63286..64389 (-) 1104 WP_053865759.1 DUF418 domain-containing protein -
  P1A14_RS00270 (P1A14_00270) - 64738..64941 (-) 204 WP_209307420.1 helix-turn-helix transcriptional regulator -
  P1A14_RS00275 (P1A14_00275) - 64952..65230 (-) 279 WP_224103024.1 DUF2975 domain-containing protein -
  P1A14_RS00280 (P1A14_00280) - 65325..65714 (-) 390 WP_049948298.1 DUF6339 family protein -
  P1A14_RS00285 (P1A14_00285) - 65773..66624 (-) 852 Protein_54 recombinase family protein -
  P1A14_RS00290 (P1A14_00290) - 66802..67059 (-) 258 WP_002434121.1 hypothetical protein -
  P1A14_RS00295 (P1A14_00295) - 67127..68917 (-) 1791 WP_031590847.1 DUF927 domain-containing protein -
  P1A14_RS00300 (P1A14_00300) - 69043..70470 (-) 1428 WP_031590850.1 DUF6038 family protein -
  P1A14_RS00305 (P1A14_00305) - 70587..71351 (+) 765 WP_031590857.1 DUF6414 family protein -
  P1A14_RS00310 (P1A14_00310) - 71341..72456 (+) 1116 WP_031590860.1 AAA family ATPase -
  P1A14_RS00315 (P1A14_00315) - 72618..73841 (+) 1224 WP_050438896.1 hypothetical protein -
  P1A14_RS00320 (P1A14_00320) - 74406..74681 (+) 276 WP_231385368.1 GNAT family N-acetyltransferase -
  P1A14_RS00325 (P1A14_00325) - 74963..75883 (+) 921 WP_224684921.1 SEFIR domain-containing protein -
  P1A14_RS00330 (P1A14_00330) - 75955..77415 (+) 1461 WP_031590866.1 DUF6038 family protein -
  P1A14_RS00335 (P1A14_00335) - 77617..78693 (+) 1077 WP_031590869.1 DNA polymerase -
  P1A14_RS00340 (P1A14_00340) - 78710..79084 (+) 375 WP_031590871.1 hypothetical protein -
  P1A14_RS00345 (P1A14_00345) - 79077..80690 (+) 1614 WP_031590872.1 DUF5906 domain-containing protein -
  P1A14_RS00350 (P1A14_00350) - 80779..80910 (+) 132 WP_256769442.1 hypothetical protein -
  P1A14_RS00355 (P1A14_00355) - 80917..82602 (+) 1686 WP_031590875.1 recombinase family protein -
  P1A14_RS00360 (P1A14_00360) - 82691..83029 (+) 339 WP_031775842.1 SAUGI family uracil-DNA glycosylase inhibitor -
  P1A14_RS00365 (P1A14_00365) - 83122..83433 (+) 312 WP_031590878.1 DUF960 family protein -
  P1A14_RS00370 (P1A14_00370) - 83449..83952 (+) 504 WP_031590880.1 DUF1643 domain-containing protein -
  P1A14_RS00375 (P1A14_00375) - 83966..84187 (+) 222 WP_031590882.1 hypothetical protein -
  P1A14_RS00380 (P1A14_00380) - 84372..85115 (+) 744 WP_031590884.1 hypothetical protein -
  P1A14_RS00385 (P1A14_00385) - 85396..86070 (-) 675 WP_001105994.1 IS6-like element IS257 family transposase -
  P1A14_RS00390 (P1A14_00390) - 86111..86218 (-) 108 Protein_75 beta-lactam sensor/signal transducer MecR1 -
  P1A14_RS00395 (P1A14_00395) mecA 86315..88324 (+) 2010 WP_078098983.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62365.04 Da        Isoelectric Point: 9.5988

>NTDB_id=798578 P1A14_RS00160 WP_058332291.1 41433..43061(-) (ccrB) [Staphylococcus aureus strain N09HSA11]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFIVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKMANALNHKGYVTKKGNPFSTSAIAYILSNPFYIGKIQFAK
YKDWNEKRRKGLNNNLVVADGKHSPIISQELWDKVHSRMKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVLKQVVERVNQDSQIDMAALNHDIAYKQQQFD
EINTKLKNLIQTIEDNPDLTSALKPTIHQYETQLNDITNQINQLKQQQNQEKPSYDTKQISNILRHIFQNIESMDKAQLK
AFYLTVIDRIDIRKDGSHKKQFFVTLKLNNEIINQLFNNTSLDEVLLSTSSLFLPQILYFQI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=798578 P1A14_RS00160 WP_058332291.1 41433..43061(-) (ccrB) [Staphylococcus aureus strain N09HSA11]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTATTGTTGTAGATGTATACGCGGATAGAGGTA
TTTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGCCAGATCGATTCTGTTATG
GTGTACAAAACAAACCGGCTAGCACGTAATACATCAGACTTGCTCAAAATTGTCGAGGATTTGCATAAACAAAACGTCGA
ATTTTTCAGTCTATCTGAACGCATGGAAGTTAATACGAGCAGTGGTAAACTTATGTTACAAATACTCGCAAGCTTTTCTG
AATTTGAAAGAAACAATATTGTCGAGAACGTATTTATGGGTCAAACCCGACGTGCTCAAGAAGGCTATTATCAAGGGAAT
TTACCACTAGGATATGATAAAATACCGGATAGTAAGCATGAACTCATGATAAACCAGCATGAAGCGAATATCGTCAAATA
TATATTTGAGTCATATGCTAAAGGTCATGGATATCGTAAAATGGCTAATGCACTTAATCATAAAGGTTATGTAACAAAGA
AAGGTAATCCATTCAGTACATCAGCTATAGCATATATCCTTTCCAATCCTTTTTACATTGGTAAAATACAATTTGCGAAA
TATAAAGATTGGAATGAAAAGCGACGTAAAGGACTTAATAATAATCTTGTAGTAGCTGACGGGAAGCATTCGCCTATCAT
TAGTCAAGAACTATGGGATAAAGTACATTCACGTATGAAGCAAGTTAGTCAAAAACCTCAAGTTCATGGAAAAGGAACCA
ATCTATTAACAGGCATCGTTCACTGTCCACAATGCGGCGCACCTATGGCCGCAAGTAATACCACTAATACACTCAAAGAT
GGTACCAAGAAGCGAATACGCTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTTATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTTCTCAAACAAGTTG
TCGAACGTGTTAATCAAGATAGTCAAATTGATATGGCTGCACTTAACCATGATATCGCATATAAGCAACAACAATTTGAT
GAAATAAACACTAAACTAAAAAATCTAATTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCAT
TCATCAATATGAAACACAACTGAATGATATCACAAACCAAATTAATCAACTCAAGCAGCAACAAAACCAAGAAAAACCAT
CTTACGATACGAAGCAAATATCCAACATCTTACGTCATATATTTCAAAACATAGAATCCATGGATAAAGCACAACTCAAA
GCATTCTACCTTACGGTCATTGATCGTATTGATATTCGTAAAGATGGAAGTCATAAAAAACAATTCTTTGTCACACTCAA
GCTCAATAATGAGATTATTAACCAACTTTTCAATAATACCTCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAATACTCTACTTTCAAATCTAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(180-281)

Resolvase, N terminal domain (Resolvase)

(11-156)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

84.133

100

0.841