Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MT340_RS04700 Genome accession   NZ_CP119327
Coordinates   975073..975702 (+) Length   209 a.a.
NCBI ID   WP_243588987.1    Uniprot ID   -
Organism   Staphylococcus sp. NRL 16/872     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 970073..980702
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MT340_RS04675 (MT340_004675) - 970761..971771 (-) 1011 WP_243588982.1 aromatic acid exporter family protein -
  MT340_RS04680 (MT340_004680) map 971919..972671 (+) 753 WP_243588983.1 type I methionyl aminopeptidase -
  MT340_RS04685 (MT340_004685) - 972924..973310 (+) 387 WP_243588984.1 hypothetical protein -
  MT340_RS04690 (MT340_004690) liaF 973339..974040 (+) 702 WP_243588985.1 cell wall-active antibiotics response protein LiaF -
  MT340_RS04695 (MT340_004695) vraS 974037..975083 (+) 1047 WP_243588986.1 sensor histidine kinase Regulator
  MT340_RS04700 (MT340_004700) vraR 975073..975702 (+) 630 WP_243588987.1 two-component system response regulator VraR Regulator
  MT340_RS04705 (MT340_004705) - 975755..976972 (-) 1218 WP_243588988.1 YihY/virulence factor BrkB family protein -
  MT340_RS04710 (MT340_004710) - 977063..977347 (-) 285 WP_243588989.1 YtxH domain-containing protein -
  MT340_RS04715 (MT340_004715) - 977353..977817 (-) 465 WP_243588990.1 low molecular weight protein-tyrosine-phosphatase -
  MT340_RS04720 (MT340_004720) - 977958..978164 (+) 207 WP_243588991.1 DUF1128 domain-containing protein -
  MT340_RS04725 (MT340_004725) - 978178..979425 (+) 1248 WP_243588992.1 aminopeptidase -
  MT340_RS04730 (MT340_004730) - 979465..979998 (+) 534 WP_243603611.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23589.31 Da        Isoelectric Point: 5.0156

>NTDB_id=798479 MT340_RS04700 WP_243588987.1 975073..975702(+) (vraR) [Staphylococcus sp. NRL 16/872]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKDAIAKAHELQPDLILMDLLMDDMDGVEATTQIKKDLPRIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIAEAVRKTYNGEAVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=798479 MT340_RS04700 WP_243588987.1 975073..975702(+) (vraR) [Staphylococcus sp. NRL 16/872]
ATGGCGATTAAAGTACTATTTGTGGATGACCACGAAATGGTTCGTATTGGAATTTCAAGTTATTTATCAACGCAAGAAGA
TATTGAAGTCGTGGGAGAAGGCGCATCCGGTAAAGATGCAATTGCTAAGGCGCATGAATTACAACCTGATTTAATATTAA
TGGATTTACTTATGGATGATATGGACGGCGTGGAAGCTACGACCCAAATAAAAAAAGATTTACCTCGCATTAAAGTAGTC
ATGCTTACAAGTTTTATAGAAGATAAAGAAGTCTATAGAGCATTAGATGCTGGGGTAGATAGTTATATTTTAAAAACAAC
AAGTGCTAAAGATATAGCTGAAGCGGTGCGTAAAACATATAACGGTGAAGCAGTATTTGAACCAGAAGTGTTAGTGAAAA
TGCGTAATAGAATGAAAAAAAGAGCAGAATTATATGAAATGTTAACTGAACGTGAAATGGAGATATTGCTACTAATTGCA
AAAGGATATTCTAACCAAGAAATAGCAAGCGCGTCTCATATTACAATCAAAACAGTGAAAACACATGTAAGTAATATACT
GAGTAAATTAGAAGTACAAGATAGAACTCAAGCTGTTATATATGCTTTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368