Detailed information NTG0798054

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: PY824_RS06305
• Genome accession: NZ_CP119172
• Coordinates: 1172823..1174052 (-)
• Length: 409 a.a.
• NCBI ID: WP_012962047.1
• Uniprot ID: -
• Organism: Streptococcus macedonicus strain SGM CIP105683
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1167823..1179052

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PY824_RS06280 (PY824_06280)	-	1168117..1168764 (+)	648	Protein_1170	deoxyribonuclease I	-
PY824_RS06285 (PY824_06285)	-	1168873..1169499 (+)	627	WP_051673280.1	YoaK family protein	-
PY824_RS06290 (PY824_06290)	mmuM	1169584..1170531 (-)	948	WP_039670872.1	homocysteine S-methyltransferase	-
PY824_RS06295 (PY824_06295)	-	1170544..1171920 (-)	1377	WP_115266096.1	amino acid permease	-
PY824_RS06300 (PY824_06300)	yihA	1172219..1172812 (-)	594	WP_014294684.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
PY824_RS06305 (PY824_06305)	clpX	1172823..1174052 (-)	1230	WP_012962047.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
PY824_RS06310 (PY824_06310)	-	1174272..1174766 (-)	495	WP_014294685.1	dihydrofolate reductase	-
PY824_RS06315 (PY824_06315)	-	1174854..1175693 (-)	840	WP_014294686.1	thymidylate synthase	-
PY824_RS06320 (PY824_06320)	-	1176015..1177193 (+)	1179	WP_014294687.1	hydroxymethylglutaryl-CoA synthase	-
PY824_RS06325 (PY824_06325)	-	1177168..1178451 (+)	1284	WP_014294688.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45154.77 Da
• Isoelectric Point: 4.5644

>NTDB_id=798054 PY824_RS06305 WP_012962047.1 1172823..1174052(-) (clpX) [Streptococcus macedonicus strain SGM CIP105683]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQDR
AKRALAVAVYNHYKRVSFAESRNEEDVDLQKSNILMIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDENASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTADDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDKDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSQEEVTKVRITKAAVEG
KDKPILEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=798054 PY824_RS06305 WP_012962047.1 1172823..1174052(-) (clpX) [Streptococcus macedonicus strain SGM CIP105683]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTCTGTGGAAAAAGCCAAGATGAAGTGAAAAAAATCAT
TGCAGGAAACAATGTTTTTATCTGTAATGAGTGCGTGGCTTTATCACAAGAAATTATCAAAGAAGAACTTGCTGAGGAAG
TTCTTGCAGATTTAGCGGAAGTTCCAAAACCTAAAGAGTTGTTAGCAACTCTTGACGAATATGTCGTTGGTCAAGACCGT
GCCAAACGCGCGCTTGCCGTAGCTGTTTATAACCATTACAAACGTGTTTCTTTTGCGGAAAGTCGCAATGAAGAAGATGT
TGATTTGCAAAAATCAAACATTTTGATGATTGGTCCTACAGGTTCAGGAAAAACATTCCTAGCTCAAACTTTGGCTAAAA
CATTGAATGTACCGTTTGCAATTGCTGATGCGACATCATTGACAGAAGCAGGATACGTTGGTGAAGATGTTGAAAATATC
CTCTTGAAATTAATTCAAGCAGCTGATTTTAATATCGAACGCGCCGAACGCGGTATCATTTACGTGGATGAAATTGATAA
AATCGCTAAAAAAGGTGAAAATGTCTCAATTACACGTGATGTTTCAGGTGAAGGTGTTCAACAAGCACTTCTTAAAATCA
TTGAAGGAACCGTTGCTAGCGTACCACCTCAAGGCGGACGTAAGCACCCTAACCAAGAAATGATTCAAATTGATACTAAA
AATATCTTATTCATTGTCGGCGGTGCTTTTGATGGTATCGAAGATATTGTCAAACAACGTTTAGGTGAAAAGGTTATCGG
TTTTGGTCAAAATAACCGTAAAATTGATGAAAATGCTTCTTATATGCAAGAAATCATTTCAGAAGACATTCAAAAATTTG
GCTTGATTCCAGAGTTTATCGGACGTTTGCCAGTTGTAGCAGCACTTGAACAGTTGACGGCTGATGATTTGGTTCGTATC
TTGACAGAACCACGTAATGCCTTGGTTAAACAATATCAAACGCTATTATCATACGACGGTGTTGAACTAGAATTTGATAA
AGATGCTTTGCAAGCTATTGCTAACAAAGCCATTGAACGTAAGACAGGAGCTCGTGGTTTACGCTCAATTATTGAAGAAA
CTATGATGGATATCATGTTTGAAATTCCTAGCCAAGAAGAAGTGACTAAGGTTCGTATCACTAAAGCGGCTGTTGAAGGC
AAAGACAAACCAATTTTGGAAATTGCGTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.976	100	0.9
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575