Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   RBH63_RS16195 Genome accession   NZ_CP132983
Coordinates   2975496..2976152 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ARS-C301     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2970496..2981152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RBH63_RS16160 dcyD 2971376..2972362 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  RBH63_RS16165 tcyL 2972377..2973045 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  RBH63_RS16170 tcyN 2973042..2973794 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  RBH63_RS16175 sdiA 2974024..2974746 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  RBH63_RS16180 yecF 2974813..2975037 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  RBH63_RS16185 yecU 2975024..2975200 (-) 177 WP_001307856.1 protein YecU -
  RBH63_RS16190 - 2975283..2975354 (-) 72 Protein_2780 transcriptional regulator -
  RBH63_RS16195 letA 2975496..2976152 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  RBH63_RS16200 uvrC 2976149..2977981 (+) 1833 WP_001283426.1 excinuclease ABC subunit UvrC Machinery gene
  RBH63_RS16205 pgsA 2978038..2978586 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  RBH63_RS16225 yecA 2979235..2979900 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=797666 RBH63_RS16195 WP_000611328.1 2975496..2976152(+) (letA) [Escherichia coli strain ARS-C301]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=797666 RBH63_RS16195 WP_000611328.1 2975496..2976152(+) (letA) [Escherichia coli strain ARS-C301]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482