Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   PZB81_RS04490 Genome accession   NZ_CP119047
Coordinates   946719..947348 (+) Length   209 a.a.
NCBI ID   WP_002473914.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain N2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 941719..952348
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PZB81_RS04460 (PZB81_04460) - 941824..942360 (+) 537 WP_002494124.1 hypothetical protein -
  PZB81_RS04465 (PZB81_04465) - 942511..943497 (-) 987 WP_002494125.1 aromatic acid exporter family protein -
  PZB81_RS04470 (PZB81_04470) map 943671..944426 (+) 756 WP_002494126.1 type I methionyl aminopeptidase -
  PZB81_RS04475 (PZB81_04475) - 944584..944970 (+) 387 WP_001830382.1 hypothetical protein -
  PZB81_RS04480 (PZB81_04480) liaF 944985..945686 (+) 702 WP_002473931.1 cell wall-active antibiotics response protein LiaF -
  PZB81_RS04485 (PZB81_04485) vraS 945683..946729 (+) 1047 WP_002494127.1 sensor histidine kinase Regulator
  PZB81_RS04490 (PZB81_04490) vraR 946719..947348 (+) 630 WP_002473914.1 two-component system response regulator VraR Regulator
  PZB81_RS04495 (PZB81_04495) - 947405..948583 (-) 1179 WP_001830411.1 YihY/virulence factor BrkB family protein -
  PZB81_RS04500 (PZB81_04500) - 948990..949274 (-) 285 WP_002473916.1 YtxH domain-containing protein -
  PZB81_RS04505 (PZB81_04505) - 949282..949746 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  PZB81_RS04510 (PZB81_04510) - 949887..950102 (+) 216 WP_002494128.1 DUF1128 domain-containing protein -
  PZB81_RS04515 (PZB81_04515) - 950104..951345 (+) 1242 WP_002494129.1 aminopeptidase -
  PZB81_RS04520 (PZB81_04520) - 951425..951955 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23598.22 Da        Isoelectric Point: 4.7218

>NTDB_id=797382 PZB81_RS04490 WP_002473914.1 946719..947348(+) (vraR) [Staphylococcus epidermidis strain N2]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=797382 PZB81_RS04490 WP_002473914.1 946719..947348(+) (vraR) [Staphylococcus epidermidis strain N2]
GTGGCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACTCAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAAGAGGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCAACTACTGAAATTAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAGGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCCTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTTCAAGATCGAACACAAGCAGTAATCTATGCGTTCCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373