Detailed information NTG0797002

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PYW39_RS04465
• Genome accession: NZ_CP118973
• Coordinates: 911186..912229 (+)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain DSM 20316
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 906186..917229

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYW39_RS04440	-	907242..907967 (+)	726	WP_002466154.1	type 1 glutamine amidotransferase	-
PYW39_RS04445	-	908035..909021 (-)	987	WP_015364857.1	FUSC family protein	-
PYW39_RS04450	map	909188..909943 (+)	756	WP_002466104.1	type I methionyl aminopeptidase	-
PYW39_RS04455	-	910087..910473 (+)	387	WP_002466133.1	DUF2543 family protein	-
PYW39_RS04460	liaF	910488..911189 (+)	702	WP_103286363.1	cell wall-active antibiotics response protein LiaF	-
PYW39_RS04465	vraS	911186..912229 (+)	1044	WP_002466111.1	sensor histidine kinase	Regulator
PYW39_RS04470	vraR	912219..912848 (+)	630	WP_002466112.1	two-component system response regulator VraR	Regulator
PYW39_RS04475	-	912907..914142 (-)	1236	WP_015364859.1	YihY/virulence factor BrkB family protein	-
PYW39_RS04480	-	914372..914656 (-)	285	WP_103286364.1	YtxH domain-containing protein	-
PYW39_RS04485	-	914663..915127 (-)	465	WP_002466141.1	low molecular weight protein-tyrosine-phosphatase	-
PYW39_RS04490	-	915274..915477 (+)	204	WP_002466135.1	DUF1128 domain-containing protein	-
PYW39_RS04495	-	915490..916731 (+)	1242	WP_015364860.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=797002 PYW39_RS04465 WP_002466111.1 911186..912229(+) (vraS) [Staphylococcus warneri strain DSM 20316]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=797002 PYW39_RS04465 WP_002466111.1 911186..912229(+) (vraS) [Staphylococcus warneri strain DSM 20316]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTCCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948