Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   PYW30_RS02230 Genome accession   NZ_CP118950
Coordinates   445651..446334 (+) Length   227 a.a.
NCBI ID   WP_004259224.1    Uniprot ID   A0A1I4FNQ8
Organism   Lactococcus garvieae subsp. garvieae strain DSM 20684     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 440651..451334
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYW30_RS02220 rpoC 440759..444406 (+) 3648 WP_004259228.1 DNA-directed RNA polymerase subunit beta' -
  PYW30_RS02225 - 444499..445407 (-) 909 WP_042217295.1 diacylglycerol kinase family protein -
  PYW30_RS02230 mecA 445651..446334 (+) 684 WP_004259224.1 adaptor protein MecA Regulator
  PYW30_RS02235 - 446338..447594 (+) 1257 WP_042217292.1 MraY family glycosyltransferase -
  PYW30_RS02240 sufC 447672..448442 (+) 771 WP_042217290.1 Fe-S cluster assembly ATPase SufC -
  PYW30_RS02245 sufD 448514..449770 (+) 1257 WP_019299087.1 Fe-S cluster assembly protein SufD -
  PYW30_RS02250 - 449770..450981 (+) 1212 WP_042217288.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26239.38 Da        Isoelectric Point: 4.0202

>NTDB_id=796680 PYW30_RS02230 WP_004259224.1 445651..446334(+) (mecA) [Lactococcus garvieae subsp. garvieae strain DSM 20684]
MQYEEINEKTIKISLTFQDLVDHDVKLSDFFTNQSMVENLFYELVEELGLEERFSSGLLTFQIQPFPKGVNIIVTEENID
IDPNNLPDDPEEFEQLMTDFFGRVEDLKQNGGTMADTSTTETKETKVENKPDPDFVFYSLEFENMSQLLTAVKNVKIDAE
ESELYSYQDKFYLIILDNQKSKGKTAVSSMRARMLEYGQETVNSRETLQEYGEILINTRALEVLSKI

Nucleotide


Download         Length: 684 bp        

>NTDB_id=796680 PYW30_RS02230 WP_004259224.1 445651..446334(+) (mecA) [Lactococcus garvieae subsp. garvieae strain DSM 20684]
ATGCAATACGAAGAAATAAACGAAAAAACGATAAAGATTAGCCTAACCTTTCAAGATTTGGTTGATCATGATGTCAAACT
CTCTGATTTTTTTACTAACCAGTCGATGGTTGAAAATCTTTTTTATGAATTAGTAGAAGAACTGGGACTTGAGGAAAGAT
TCTCATCAGGACTTTTAACTTTCCAAATTCAACCTTTCCCTAAAGGGGTGAATATCATTGTTACCGAGGAAAATATTGAT
ATTGATCCCAATAATCTCCCGGATGATCCTGAAGAATTTGAGCAGCTGATGACGGATTTCTTTGGGCGTGTGGAAGATTT
AAAACAAAATGGCGGAACAATGGCAGATACAAGTACAACTGAAACGAAAGAAACAAAAGTAGAAAATAAACCAGACCCAG
ATTTTGTCTTCTATTCTCTAGAATTTGAAAATATGTCTCAACTTTTGACAGCTGTAAAAAATGTTAAAATTGATGCAGAA
GAGTCTGAACTTTACAGTTACCAAGATAAGTTTTATTTGATTATTTTGGACAATCAAAAATCAAAAGGAAAAACAGCCGT
AAGTTCGATGCGTGCTCGAATGTTAGAATATGGCCAGGAAACGGTCAACAGTCGTGAAACCCTACAAGAATACGGCGAGA
TACTAATCAATACGCGTGCTTTGGAAGTTCTCTCAAAAATTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4FNQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. cremoris KW2

54.661

100

0.568
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

54.077

100

0.555