Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   RAM31_RS09570 Genome accession   NZ_CP132368
Coordinates   2019498..2020760 (-) Length   420 a.a.
NCBI ID   WP_306178526.1    Uniprot ID   -
Organism   Staphylococcus aureus strain UNC_SA44     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2014498..2025760
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RAM31_RS09545 (RAM31_09540) - 2014696..2015364 (-) 669 WP_000805950.1 uroporphyrinogen-III synthase -
  RAM31_RS09550 (RAM31_09545) hemC 2015386..2016312 (-) 927 WP_001230226.1 hydroxymethylbilane synthase -
  RAM31_RS09555 (RAM31_09550) ccsA 2016354..2017169 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  RAM31_RS09560 (RAM31_09555) hemA 2017191..2018537 (-) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  RAM31_RS09565 (RAM31_09560) yihA 2018754..2019344 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  RAM31_RS09570 (RAM31_09565) clpX 2019498..2020760 (-) 1263 WP_306178526.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  RAM31_RS09575 (RAM31_09570) tig 2020911..2022212 (-) 1302 WP_000127573.1 trigger factor -
  RAM31_RS09580 (RAM31_09575) - 2022260..2022370 (-) 111 WP_001790560.1 hypothetical protein -
  RAM31_RS09585 (RAM31_09580) - 2022375..2023304 (-) 930 WP_001280022.1 hypothetical protein -
  RAM31_RS09590 (RAM31_09585) - 2023323..2023931 (-) 609 WP_000032650.1 NUDIX domain-containing protein -
  RAM31_RS09595 (RAM31_09590) rplT 2024073..2024429 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  RAM31_RS09600 (RAM31_09595) rpmI 2024476..2024676 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  RAM31_RS09605 (RAM31_09600) infC 2024705..2025232 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46308.55 Da        Isoelectric Point: 4.2827

>NTDB_id=796478 RAM31_RS09570 WP_306178526.1 2019498..2020760(-) (clpX) [Staphylococcus aureus strain UNC_SA44]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDNVDLEFIEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=796478 RAM31_RS09570 WP_306178526.1 2019498..2020760(-) (clpX) [Staphylococcus aureus strain UNC_SA44]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATGACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATAATGTGGATTTAGAGTTCATTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.75

95.238

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531