Detailed information    

insolico Bioinformatically predicted

Overview

Name   comO   Type   Machinery gene
Locus tag   HIY_RS00260 Genome accession   NZ_AP022867
Coordinates   55925..56641 (-) Length   238 a.a.
NCBI ID   WP_005655922.1    Uniprot ID   A0A0H3PFM8
Organism   Haemophilus influenzae strain 2018-Y40     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 50925..61641
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIY_RS00240 (HIY_00480) nrdR 51015..51464 (-) 450 WP_005651549.1 transcriptional regulator NrdR -
  HIY_RS00245 (HIY_00490) recC 51527..54901 (-) 3375 WP_005655932.1 exodeoxyribonuclease V subunit gamma -
  HIY_RS00250 (HIY_00500) comQ 54947..55234 (-) 288 WP_005655928.1 DUF5374 domain-containing protein Machinery gene
  HIY_RS00255 (HIY_00510) comP 55227..55910 (-) 684 WP_005655925.1 DUF2572 family protein Machinery gene
  HIY_RS00260 (HIY_00520) comO 55925..56641 (-) 717 WP_005655922.1 type II secretion system protein J Machinery gene
  HIY_RS00265 (HIY_00530) comN 56641..57153 (-) 513 WP_005651545.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  HIY_RS00270 (HIY_00540) suhB 57353..58156 (+) 804 WP_005655917.1 inositol-1-monophosphatase -
  HIY_RS00275 (HIY_00550) nrfE 58264..60171 (+) 1908 WP_005655914.1 heme lyase NrfEFG subunit NrfE -
  HIY_RS00280 (HIY_00560) - 60171..60701 (+) 531 WP_005655912.1 DsbE family thiol:disulfide interchange protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 26734.11 Da        Isoelectric Point: 9.5507

>NTDB_id=79547 HIY_RS00260 WP_005655922.1 55925..56641(-) (comO) [Haemophilus influenzae strain 2018-Y40]
MMKVLLKGQTLLALMISLALSSLLLLSISHFYVQIQTQNQQMLLHLKLQAELQRTLQLIGKDLRRLGFRALNAKLTESNL
SLFELDEQGTAIFISQEDNAPPNSCVLFFYDLNKNGCIGKGSPKTCMKKGKNTSKSSTEELFGYKVSNKMIKTKLTYQSV
IPTNCTAETCKRAFQQTACNAGGGWADLLDNNEYEITRLQFNWLIEGKGLEIKLKGNLKQTPNISYETSLVVALWNQK

Nucleotide


Download         Length: 717 bp        

>NTDB_id=79547 HIY_RS00260 WP_005655922.1 55925..56641(-) (comO) [Haemophilus influenzae strain 2018-Y40]
ATGATGAAAGTATTATTAAAAGGGCAAACCCTATTAGCGCTGATGATTTCACTAGCATTGTCGTCTTTATTATTGCTAAG
CATTTCGCATTTTTATGTGCAAATACAAACGCAAAATCAACAGATGTTATTACATTTAAAATTACAAGCTGAATTACAAC
GAACATTACAGTTAATAGGTAAAGATCTTCGCCGATTAGGATTTCGAGCATTAAATGCAAAACTGACGGAAAGCAATTTA
TCTTTATTTGAATTAGATGAACAAGGCACAGCTATTTTTATTAGCCAAGAAGATAATGCACCACCTAATAGCTGCGTGTT
GTTCTTTTATGATTTAAATAAAAATGGGTGTATTGGCAAAGGTTCGCCGAAAACCTGTATGAAAAAAGGTAAAAATACAT
CTAAAAGTAGTACTGAAGAATTATTCGGCTATAAAGTGAGTAACAAAATGATAAAAACCAAACTGACTTATCAAAGTGTT
ATTCCTACTAATTGCACGGCAGAAACTTGTAAACGTGCTTTTCAACAAACCGCTTGTAACGCTGGTGGTGGATGGGCAGA
TTTATTAGATAACAACGAATATGAAATCACTAGGTTACAATTTAATTGGTTAATTGAAGGCAAAGGATTAGAAATCAAGC
TAAAAGGAAATTTAAAACAAACCCCAAATATCAGTTATGAAACATCCCTTGTTGTTGCGCTATGGAATCAAAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3PFM8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comO Haemophilus influenzae Rd KW20

98.739

100

0.987

Multiple sequence alignment