Detailed information NTG0795436

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PYH73_RS09590
• Genome accession: NZ_CP118808
• Coordinates: 1938824..1939867 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 7063
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1933824..1944867

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYH73_RS09560 (PYH73_09560)	-	1934246..1935502 (-)	1257	WP_072398252.1	aminopeptidase	-
PYH73_RS09565 (PYH73_09565)	-	1935505..1935705 (-)	201	WP_000180460.1	DUF1128 family protein	-
PYH73_RS09570 (PYH73_09570)	-	1935852..1936316 (+)	465	WP_000567539.1	low molecular weight protein-tyrosine-phosphatase	-
PYH73_RS09575 (PYH73_09575)	-	1936323..1936598 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
PYH73_RS09580 (PYH73_09580)	-	1936876..1938093 (+)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
PYH73_RS09585 (PYH73_09585)	vraR	1938205..1938834 (-)	630	WP_000153532.1	two-component system response regulator VraR	Regulator
PYH73_RS09590 (PYH73_09590)	vraS	1938824..1939867 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
PYH73_RS09595 (PYH73_09595)	liaF	1939864..1940565 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
PYH73_RS09600 (PYH73_09600)	-	1940580..1940966 (-)	387	WP_001110179.1	hypothetical protein	-
PYH73_RS09605 (PYH73_09605)	map	1941183..1941941 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
PYH73_RS09610 (PYH73_09610)	-	1942413..1943399 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
PYH73_RS09615 (PYH73_09615)	-	1943830..1944243 (-)	414	WP_025175030.1	hypothetical protein	-
PYH73_RS09620 (PYH73_09620)	-	1944272..1944382 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=795436 PYH73_RS09590 WP_001017131.1 1938824..1939867(-) (vraS) [Staphylococcus aureus strain 7063]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=795436 PYH73_RS09590 WP_001017131.1 1938824..1939867(-) (vraS) [Staphylococcus aureus strain 7063]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTGAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1