Detailed information NTG0795315

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PYH52_RS04540
• Genome accession: NZ_CP118794
• Coordinates: 939132..940175 (+)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain 7067
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 934132..945175

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYH52_RS04515 (PYH52_04515)	-	935188..935913 (+)	726	WP_002466154.1	type 1 glutamine amidotransferase	-
PYH52_RS04520 (PYH52_04520)	-	935981..936967 (-)	987	WP_031464159.1	aromatic acid exporter family protein	-
PYH52_RS04525 (PYH52_04525)	map	937134..937889 (+)	756	WP_002466104.1	type I methionyl aminopeptidase	-
PYH52_RS04530 (PYH52_04530)	-	938033..938419 (+)	387	WP_002466133.1	DUF2543 family protein	-
PYH52_RS04535 (PYH52_04535)	liaF	938434..939135 (+)	702	WP_002466140.1	cell wall-active antibiotics response protein LiaF	-
PYH52_RS04540 (PYH52_04540)	vraS	939132..940175 (+)	1044	WP_002466111.1	sensor histidine kinase	Regulator
PYH52_RS04545 (PYH52_04545)	vraR	940165..940794 (+)	630	WP_002466112.1	two-component system response regulator VraR	Regulator
PYH52_RS04550 (PYH52_04550)	-	940853..942088 (-)	1236	WP_002466159.1	YihY/virulence factor BrkB family protein	-
PYH52_RS04555 (PYH52_04555)	-	942318..942602 (-)	285	WP_002466132.1	YtxH domain-containing protein	-
PYH52_RS04560 (PYH52_04560)	-	942609..943073 (-)	465	WP_002466141.1	low molecular weight protein-tyrosine-phosphatase	-
PYH52_RS04565 (PYH52_04565)	-	943220..943423 (+)	204	WP_002466135.1	DUF1128 domain-containing protein	-
PYH52_RS04570 (PYH52_04570)	-	943436..944677 (+)	1242	WP_002466147.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=795315 PYH52_RS04540 WP_002466111.1 939132..940175(+) (vraS) [Staphylococcus warneri strain 7067]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=795315 PYH52_RS04540 WP_002466111.1 939132..940175(+) (vraS) [Staphylococcus warneri strain 7067]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTCCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948