Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   QFX49_RS08625 Genome accession   NZ_CP132038
Coordinates   1710177..1711439 (+) Length   420 a.a.
NCBI ID   WP_000472302.1    Uniprot ID   P63789
Organism   Staphylococcus aureus strain 1.6     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1705177..1716439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX49_RS08590 infC 1705705..1706232 (+) 528 WP_001791162.1 translation initiation factor IF-3 -
  QFX49_RS08595 rpmI 1706261..1706461 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  QFX49_RS08600 rplT 1706508..1706864 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  QFX49_RS08605 - 1707006..1707614 (+) 609 WP_000032657.1 NUDIX domain-containing protein -
  QFX49_RS08610 - 1707633..1708562 (+) 930 WP_001280018.1 hypothetical protein -
  QFX49_RS08615 - 1708567..1708677 (+) 111 WP_001790560.1 hypothetical protein -
  QFX49_RS08620 tig 1708725..1710026 (+) 1302 WP_000127573.1 trigger factor -
  QFX49_RS08625 clpX 1710177..1711439 (+) 1263 WP_000472302.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  QFX49_RS08630 yihA 1711593..1712183 (+) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  QFX49_RS08635 hemA 1712400..1713746 (+) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  QFX49_RS08640 ccsA 1713768..1714583 (+) 816 WP_001157329.1 cytochrome c biogenesis protein -
  QFX49_RS08645 hemC 1714625..1715551 (+) 927 WP_001230228.1 hydroxymethylbilane synthase -
  QFX49_RS08650 - 1715573..1716241 (+) 669 WP_000805950.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46297.48 Da        Isoelectric Point: 4.2645

>NTDB_id=795152 QFX49_RS08625 WP_000472302.1 1710177..1711439(+) (clpX) [Staphylococcus aureus strain 1.6]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=795152 QFX49_RS08625 WP_000472302.1 1710177..1711439(+) (clpX) [Staphylococcus aureus strain 1.6]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATGACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACCTTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63789

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531