Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   PWP91_RS10800 Genome accession   NZ_CP118738
Coordinates   2165332..2166033 (-) Length   233 a.a.
NCBI ID   WP_004255173.1    Uniprot ID   S6FFV7
Organism   Lactococcus lactis strain P-1     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2160332..2171033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWP91_RS10780 (PWP91_10780) - 2160442..2161659 (-) 1218 WP_274998532.1 cysteine desulfurase -
  PWP91_RS10785 (PWP91_10785) sufD 2161659..2162915 (-) 1257 WP_200095170.1 Fe-S cluster assembly protein SufD -
  PWP91_RS10790 (PWP91_10790) sufC 2163053..2163823 (-) 771 WP_004255181.1 Fe-S cluster assembly ATPase SufC -
  PWP91_RS10795 (PWP91_10795) - 2163998..2165329 (-) 1332 WP_021722251.1 glycosyltransferase family 4 protein -
  PWP91_RS10800 (PWP91_10800) mecA 2165332..2166033 (-) 702 WP_004255173.1 adaptor protein MecA Regulator
  PWP91_RS10805 (PWP91_10805) - 2166163..2166897 (-) 735 WP_058203972.1 amino acid ABC transporter ATP-binding protein -
  PWP91_RS10810 (PWP91_10810) - 2166897..2167583 (-) 687 WP_058203973.1 amino acid ABC transporter permease -
  PWP91_RS10815 (PWP91_10815) - 2167730..2168638 (-) 909 WP_033899919.1 diacylglycerol/lipid kinase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27077.46 Da        Isoelectric Point: 4.1246

>NTDB_id=794818 PWP91_RS10800 WP_004255173.1 2165332..2166033(-) (mecA) [Lactococcus lactis strain P-1]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=794818 PWP91_RS10800 WP_004255173.1 2165332..2166033(-) (mecA) [Lactococcus lactis strain P-1]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGTT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTTGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FFV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.571

100

0.996
  mecA Lactococcus lactis subsp. cremoris KW2

96.996

100

0.97