Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   PW252_RS09035 Genome accession   NZ_CP118735
Coordinates   1849417..1850106 (-) Length   229 a.a.
NCBI ID   WP_248051330.1    Uniprot ID   A0AA97A3U6
Organism   Streptococcus iners strain 29887     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1844417..1855106
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS09010 (PW252_09015) - 1844883..1845596 (-) 714 WP_248051321.1 nitroreductase family protein -
  PW252_RS09015 (PW252_09020) dnaI 1845593..1846492 (-) 900 WP_248051323.1 primosomal protein DnaI -
  PW252_RS09020 (PW252_09025) - 1846492..1847643 (-) 1152 WP_248051326.1 replication initiation/membrane attachment protein -
  PW252_RS09025 (PW252_09030) nrdR 1847630..1848121 (-) 492 WP_105117716.1 transcriptional regulator NrdR -
  PW252_RS09030 (PW252_09035) - 1848219..1849343 (-) 1125 WP_248051328.1 AI-2E family transporter -
  PW252_RS09035 (PW252_09040) covR 1849417..1850106 (-) 690 WP_248051330.1 DNA-binding response regulator Regulator
  PW252_RS09040 (PW252_09045) gndA 1850341..1851768 (-) 1428 WP_172028260.1 NADP-dependent phosphogluconate dehydrogenase -
  PW252_RS09045 (PW252_09050) - 1851856..1852395 (-) 540 WP_172028261.1 YceD family protein -
  PW252_RS09050 (PW252_09055) trxB 1852405..1853322 (-) 918 WP_248051333.1 thioredoxin-disulfide reductase -
  PW252_RS09055 (PW252_09060) - 1853334..1853558 (-) 225 WP_172028263.1 DUF4059 family protein -
  PW252_RS09060 (PW252_09065) - 1853576..1854919 (-) 1344 WP_248051336.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26186.17 Da        Isoelectric Point: 6.7336

>NTDB_id=794749 PW252_RS09035 WP_248051330.1 1849417..1850106(-) (covR) [Streptococcus iners strain 29887]
MAKKILIAGRERNLSHFVSMELQKKEYLVDYASTGKEVLSLAHETDFDLILMSFQLSDMSSKDLSRELLAIKPASVLIVA
IDSADVAKYGEEVLSYAVSYVVKPFVISELVEQIAAIFRGRDFIDRNCKHVPMQAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYETTSETNVVDVYIRYLRGKLDVTGKPSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=794749 PW252_RS09035 WP_248051330.1 1849417..1850106(-) (covR) [Streptococcus iners strain 29887]
ATGGCTAAGAAAATTTTAATTGCAGGAAGAGAGCGCAATCTTTCGCACTTTGTTTCCATGGAATTACAGAAGAAGGAGTA
TTTGGTAGACTACGCTTCAACAGGGAAAGAAGTCCTATCTTTAGCTCATGAAACAGATTTTGACTTGATTTTGATGAGTT
TTCAGCTGTCGGATATGTCCAGTAAAGACTTGTCCAGAGAGTTGCTCGCAATCAAGCCTGCTAGTGTGTTGATTGTGGCC
ATTGATTCAGCTGATGTTGCCAAATATGGAGAAGAAGTGCTTTCATACGCAGTTTCTTATGTTGTAAAACCCTTCGTTAT
TAGTGAATTGGTTGAGCAAATTGCAGCCATCTTCCGTGGGCGAGATTTTATTGATAGAAACTGTAAACATGTTCCTATGC
AGGCGGCCTATCGTGACCTAAAGGTCGATTTTCAAAATCGAACAGTTACTCGTGGGGATGAGTTGATTAACCTGACCAGA
CGCGAATATGATTTGCTTGCAACTCTGATGAACAGCCCCGAACCTGTCAGCCGAGAACAATTGCTAGAGCGGGTTTGGAA
GTACGAAACGACTTCAGAAACTAATGTAGTAGATGTATATATTCGTTATTTACGTGGAAAATTAGATGTTACTGGTAAAC
CATCTTACATCAAGACTGTTCGTGGCGTTGGCTATGCCATGCGAGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(6-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

50.431

100

0.511
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.913

100

0.441