Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   PW220_RS02020 Genome accession   NZ_CP118734
Coordinates   384890..385579 (+) Length   229 a.a.
NCBI ID   WP_248055914.1    Uniprot ID   A0AA96VHC8
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 379890..390579
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS01995 (PW220_01995) - 380232..381575 (+) 1344 WP_024406634.1 DEAD/DEAH box helicase -
  PW220_RS02000 (PW220_02000) - 381593..381817 (+) 225 WP_105114041.1 DUF4059 family protein -
  PW220_RS02005 (PW220_02005) trxB 381829..382746 (+) 918 WP_248055916.1 thioredoxin-disulfide reductase -
  PW220_RS02010 (PW220_02010) - 382756..383295 (+) 540 WP_248055915.1 YceD family protein -
  PW220_RS02015 (PW220_02015) gndA 383383..384810 (+) 1428 WP_105114044.1 NADP-dependent phosphogluconate dehydrogenase -
  PW220_RS02020 (PW220_02020) covR 384890..385579 (+) 690 WP_248055914.1 response regulator transcription factor Regulator
  PW220_RS02025 (PW220_02025) - 385653..386777 (+) 1125 WP_248055913.1 AI-2E family transporter -
  PW220_RS02030 (PW220_02030) nrdR 386875..387366 (+) 492 WP_248055912.1 transcriptional regulator NrdR -
  PW220_RS02035 (PW220_02035) - 387353..388504 (+) 1152 WP_248055911.1 replication initiation/membrane attachment protein -
  PW220_RS02040 (PW220_02040) dnaI 388504..389403 (+) 900 WP_248055910.1 primosomal protein DnaI -
  PW220_RS02045 (PW220_02045) - 389400..390053 (+) 654 WP_248055909.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26112.07 Da        Isoelectric Point: 6.7336

>NTDB_id=794677 PW220_RS02020 WP_248055914.1 384890..385579(+) (covR) [Streptococcus iners subsp. hyiners strain 29892]
MAKKILIAGRERNLSHFVSMELQKKEYLVDYASTGKEALSLAHETDFDLILMSFQLSDMSSKELSRELLAIKPASVLIVA
IDSADVAKYGEEVLSYAVSYVVKPFVISDLVEQIAAIFRGRDFIDKNCKHVPLQAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYETTSETNVVDVYIRYLRGKLDVTGKPSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=794677 PW220_RS02020 WP_248055914.1 384890..385579(+) (covR) [Streptococcus iners subsp. hyiners strain 29892]
ATGGCTAAGAAAATTTTGATTGCCGGAAGAGAGCGCAATCTTTCGCACTTTGTTTCCATGGAGCTGCAGAAGAAGGAGTA
TTTGGTAGATTATGCCTCAACAGGGAAAGAAGCCCTCTCCTTAGCTCATGAAACGGATTTTGATTTGATTTTGATGAGCT
TTCAGCTTTCTGATATGTCTAGTAAGGAATTGTCAAGGGAATTGTTGGCCATCAAGCCTGCTAGTGTCTTGATTGTGGCC
ATTGATTCAGCTGATGTTGCCAAATATGGAGAAGAAGTGCTTTCATACGCAGTTTCTTATGTCGTCAAGCCCTTTGTCAT
CAGTGATTTGGTTGAGCAAATTGCAGCCATCTTCCGTGGGCGAGATTTTATTGATAAGAATTGTAAGCACGTTCCTTTGC
AAGCAGCCTATCGTGACCTAAAGGTCGATTTTCAAAATCGAACCGTTACTCGTGGGGATGAGTTGATTAACCTGACCAGA
CGCGAATATGATTTGCTTGCAACTCTGATGAACAGCCCCGAACCTGTCAGCCGAGAACAATTGCTAGAGCGAGTTTGGAA
ATATGAAACGACATCGGAAACTAATGTAGTAGATGTATATATTCGTTATTTACGTGGAAAATTAGATGTTACCGGTAAAC
CATCTTACATCAAGACAGTTCGTGGCGTTGGTTATGCCATGCGAGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

50.431

100

0.511
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.913

100

0.441