Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   Q7614_RS06300 Genome accession   NZ_CP131719
Coordinates   1219454..1221283 (+) Length   609 a.a.
NCBI ID   WP_075985572.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2016S09-327     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1214454..1226283
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7614_RS06285 (Q7614_06295) msbA 1215639..1217402 (+) 1764 WP_005649789.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  Q7614_RS06290 (Q7614_06300) lpxK 1217475..1218473 (+) 999 WP_005649790.1 tetraacyldisaccharide 4'-kinase -
  Q7614_RS06295 (Q7614_06305) kdsB 1218544..1219308 (+) 765 WP_075985573.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  Q7614_RS06300 (Q7614_06310) uvrC 1219454..1221283 (+) 1830 WP_075985572.1 excinuclease ABC subunit UvrC Machinery gene
  Q7614_RS06305 (Q7614_06315) - 1221381..1222094 (+) 714 WP_005649796.1 TerC family protein -
  Q7614_RS06310 (Q7614_06320) uxuA 1222147..1223331 (-) 1185 WP_005667994.1 mannonate dehydratase -
  Q7614_RS06315 (Q7614_06325) - 1223359..1224108 (-) 750 WP_005649802.1 GntR family transcriptional regulator -
  Q7614_RS06320 (Q7614_06330) - 1224269..1225297 (+) 1029 WP_005667996.1 alcohol dehydrogenase catalytic domain-containing protein -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 69603.48 Da        Isoelectric Point: 9.3955

>NTDB_id=792318 Q7614_RS06300 WP_075985572.1 1219454..1221283(+) (uvrC) [Haemophilus influenzae strain 2016S09-327]
MFNPKKFLADVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTTLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGSKKFTGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLSEQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQLKQSSRMSERYQALCDLLNLPKIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQVLQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISPKLAERIFETLKND

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=792318 Q7614_RS06300 WP_075985572.1 1219454..1221283(+) (uvrC) [Haemophilus influenzae strain 2016S09-327]
ATGTTCAATCCCAAAAAATTCCTCGCGGATGTCTCTCACGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTTGGGAAAGCAAAGGATTTAAAAAAACGTCTTTCAAGCTATTTTCGTAAAAATCTGAGCAGTAAAAAAACAG
AGGCGTTGGTGGCGTCAATTCATCATATTGACACCACGTTAACTTCATCTGAAACGGAAGCTTTACTGCTAGAGCATAAT
TTTATCAAGCTTTATCAGCCTCGCTATAACGTATTATTGCGTGATGATAAATCCTATCCATTTATTTTATTAACCAAAGA
ACGCCACCCAAGAATTACTTCTTATCGTGGTTCTAAAAAATTTACAGGCGAATATTTCGGGCCTTATCCTCACGCGGGAG
CTGTGCGTGAAACTTTGTCGCTTTTGCAAAAACTTTTTCCTGTTCGCCAATGTGAAAATTCCGTTTATTCCAACCGTTCT
CGTCCTTGTTTGCAATATCAAATTGGGCGTTGTTCTGCGCCTTGTGTACAGGGATATGTTTCTGATGAAGAATATAATCA
GCAAGTTGAATTAGCTCGCTTATTTTTACAAGGCAAAGATCAACAGGTGTTAGATTATTTAATCGGTAAAATGGAGCAGG
CAAGCAGAAATTTAGATTTTGAACAGGCTGCTCGTTATCGCGATCAAATTCAGGCTGTGCGTTCGGTTATAGAAAAACAA
TTTGTATCCAATGAACGTTTAGATGATATGGATATTATGTCTATCGCTTACCAACACGGGTTAGCCTGTGTACAGGTGAT
GTTTATTCGTCAAGGAAAAGTGCTAGGCAATCGCAGTTATTTCCCAAAAGTCCCCGCCAATACGGATTTATCGGAACTTA
CCGAAACTTTTGTGGGGCAATTTTATTTACAAGGTCATCAAGGACGAAGTATCCCGAATAGCATTATTGTGGATCGTCAA
TTAGCTGAAAAATCGGAGCTTGAGCAACTTCTTAGCGAGCAAGCGGGCAGAAAAGTGACGATTCAAGAAAGCGTAAAAGG
CGATAAAAGTAAATACTTACAGCTCGCACAAGTTAATGCTAAAGCGGCTTTAAATGTACAACTTAAACAATCTTCACGAA
TGTCAGAGCGTTATCAAGCGTTGTGTGATCTGTTAAATCTTCCTAAAATTAAGCGTATGGAATGTTTCGATATAAGCCAC
ACGATGGGAAATCAAACAGTCGCATCTTGTGTTGTTTTTAATCAAGAAGGTCCACTAAAATCTGATTATCGTCGTTTTAA
TATTGAAGGCATTACTGGCGGGGATGATTATGCTGCGATGGAACAAGTGTTGCAGAAACGTTATGAGCGTGATTTAGAAG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGAAAAGGGCAATTAAATCGTGCGCTGAATGTATTCCAACATCTT
CAAGTAAAATGGGATAAAAATAGACCGCACTTAATTGGCGTGGCAAAAGGTGTGGATCGTCGAGCAGGACAGGAAGTACT
GATCATCAGCAAACAAGACCGCGAAATTCATTTGCCTGATGATAGTTTGGCATTGCATTTGATTCAACACATCCGTGATG
AAAGCCATAATCACGCAATAAGCGGACACCGTAAAAAACGTCAAAAAGCCTTTACACAAAGTGGTTTAGAAACCATTGAA
GGTGTGGGAGCTAAACGTCGTCAGGCTTTACTGAAATATCTTGGTGGTTTACAAGGTGTGAAAAAGGCGACCTTAGATGA
AATAGCCTCTGTACCGGGCATTTCCCCTAAACTTGCTGAAAGGATTTTTGAAACGCTTAAAAACGACTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(210-234)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

Helix-hairpin-helix domain (HHH_5)

(556-607)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.815

97.701

0.369
  uvrC Streptococcus pneumoniae R6

37.479

97.701

0.366
  uvrC Streptococcus pneumoniae D39

37.479

97.701

0.366