Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   Q7616_RS06195 Genome accession   NZ_CP131717
Coordinates   1194391..1196220 (+) Length   609 a.a.
NCBI ID   WP_118806776.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2016N21-284     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1189391..1201220
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7616_RS06180 (Q7616_06185) msbA 1190720..1192483 (+) 1764 WP_005663238.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  Q7616_RS06185 (Q7616_06190) lpxK 1192556..1193554 (+) 999 WP_118806774.1 tetraacyldisaccharide 4'-kinase -
  Q7616_RS06190 (Q7616_06195) kdsB 1193625..1194389 (+) 765 WP_118806775.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  Q7616_RS06195 (Q7616_06200) uvrC 1194391..1196220 (+) 1830 WP_118806776.1 excinuclease ABC subunit UvrC Machinery gene
  Q7616_RS06200 (Q7616_06205) - 1196318..1197031 (+) 714 WP_118806777.1 TerC family protein -
  Q7616_RS06205 (Q7616_06210) uxuA 1197084..1198268 (-) 1185 WP_005667994.1 mannonate dehydratase -
  Q7616_RS06210 (Q7616_06215) - 1198288..1199043 (-) 756 WP_118806778.1 FCD domain-containing protein -
  Q7616_RS06215 (Q7616_06220) - 1199144..1199416 (-) 273 WP_005672668.1 IS1595 family transposase -
  Q7616_RS06220 (Q7616_06225) - 1199771..1200616 (+) 846 WP_112119546.1 SDR family oxidoreductase -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 69491.40 Da        Isoelectric Point: 9.0468

>NTDB_id=792189 Q7616_RS06195 WP_118806776.1 1194391..1196220(+) (uvrC) [Haemophilus influenzae strain 2016N21-284]
MFDAKKFLADVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTMLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGSKKFAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQLVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLTEQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQLKQSSRMSERYQALCDLLNLPEIKRMECFDISH
TMGNQTIASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVLQHL
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISLKLAETIFETLKND

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=792189 Q7616_RS06195 WP_118806776.1 1194391..1196220(+) (uvrC) [Haemophilus influenzae strain 2016N21-284]
ATGTTTGATGCTAAAAAGTTCTTAGCGGATGTCTCTCACGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTTGGGAAAGCAAAGGATCTAAAAAAACGTCTTTCAAGCTATTTTCGTAAAAATCTGAGTAGTAAAAAAACAG
AGGCGTTGGTGGCATCAATTCATCATATTGACACCATGCTAACTTCATCTGAAACGGAAGCTTTACTGCTAGAGCATAAT
TTTATCAAGCTTTATCAGCCTCGCTATAACGTATTATTGCGTGATGATAAATCCTATCCATTTATTTTATTAACCAAAGA
ACGTCATCCAAGAATCACTTCCTATCGTGGGTCTAAAAAATTTGCGGGTGAATATTTCGGGCCTTATCCTCACGCAGGCG
CCGTGCGTGAAACCTTATCACTTTTGCAAAAACTTTTCCCTGTTCGACAATGTGAAAATTCCGTTTATTCCAACCGCTCT
CGTCCTTGTTTGCAATATCAAATTGGGCGTTGTTCTGCGCCTTGTGTACAGGGATATGTTTCTGATGAAGAATATAACCA
GCAAGTTGAATTAGCCCGCTTATTTTTACAAGGCAAAGATCAACTGGTGTTAGATTATTTAATCGGGAAAATGGAGCAGG
CAAGCAGAAATTTAGATTTTGAACAGGCGGCTCGTTATCGTGATCAGATTCAGGCGGTGCGTTCGGTTATTGAAAAACAA
TTTGTATCCAATGAACGTTTAGATGATATGGATATTATGTCCATCGCTTACCAACACGGTTTGGCTTGTGTACAAGTGAT
GTTCATTCGTCAAGGAAAAGTGCTAGGCAATCGCAGTTACTTCCCAAAAGTCCCTGCCAATACGGATTTATCGGAACTTA
CCGAAACTTTTGTGGGACAATTTTATTTACAAGGTCATCAAGGGCGAAGTATCCCGAATAGTATTATTGTTGATCGTCAA
TTAGCTGAAAAATCAGAGCTTGAGCAACTTCTTACGGAGCAAGCAGGCAGAAAAGTGACGATTCAAGAAAGTGTAAAAGG
CGATAAGAGTAAATACTTACAGCTCGCACAAGTTAATGCTAAAGCGGCTTTAAATGTACAACTTAAACAATCTTCACGAA
TGTCAGAGCGTTATCAAGCGTTGTGTGATCTGTTAAATCTCCCTGAAATTAAGCGTATGGAGTGTTTCGATATAAGCCAC
ACGATGGGAAATCAAACGATAGCATCTTGTGTTGTTTTTAATCAAGAAGGCCCACTGAAATCTGATTATCGTCGTTTTAA
TATTGAAGGCATTACTGGTGGGGATGATTATGCAGCAATGGAACAAGCGTTGCAGAAACGTTATGAGCGTGATTTAGAAG
AAGATAAAATTCCTGATATTATTTTTATTGATGGTGGAAAAGGGCAATTAAATCGTGCGCTGAACGTGCTCCAACATCTT
CAAGTAAAATGGGATAAAAATAGACCGCACTTAATTGGCGTGGCAAAAGGTGTGGATCGTCGAGCAGGGCAGGAAGTACT
GATCATCAGCAAACAAGACCGCGAAATTCATTTGCCTGATGATAGTTTGGCATTGCATTTGATTCAACACATCCGTGATG
AAAGTCATAATCACGCAATAAGCGGACACCGTAAAAAACGTCAAAAAGCCTTTACACAAAGTGGTTTAGAAACGATTGAA
GGTGTGGGTGCTAAACGTCGTCAGGCTTTACTGAAATATCTTGGCGGTTTACAAGGTGTGAAAAAGGCGACCTTAGATGA
AATAGCCTCTGTACCGGGAATTTCCCTTAAACTTGCTGAAACGATTTTTGAAACGCTCAAAAACGATTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(210-234)

Helix-hairpin-helix domain (HHH_5)

(556-607)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.479

97.701

0.366
  uvrC Streptococcus pneumoniae R6

37.143

97.701

0.363
  uvrC Streptococcus pneumoniae D39

37.143

97.701

0.363