Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   Q7618_RS02960 Genome accession   NZ_CP131715
Coordinates   577182..579026 (+) Length   614 a.a.
NCBI ID   WP_001061170.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 2006C08-243     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 572182..584026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7618_RS02940 (Q7618_02930) - 573014..573793 (+) 780 WP_000290001.1 alpha/beta hydrolase family protein -
  Q7618_RS02945 (Q7618_02935) murM 573905..575125 (+) 1221 WP_000286563.1 peptidoglycan bridge formation alanyltransferase MurM -
  Q7618_RS02950 (Q7618_02940) murN 575130..576362 (+) 1233 WP_001229505.1 peptidoglycan bridge formation alanyltransferase MurN -
  Q7618_RS02955 (Q7618_02945) - 576441..577142 (+) 702 WP_001267410.1 M57 family metalloprotease -
  Q7618_RS02960 (Q7618_02950) uvrC 577182..579026 (+) 1845 WP_001061170.1 excinuclease ABC subunit UvrC Machinery gene
  Q7618_RS02965 (Q7618_02955) - 579016..579849 (+) 834 WP_001015778.1 metallophosphoesterase family protein -
  Q7618_RS02970 (Q7618_02960) - 580031..580831 (-) 801 WP_000714633.1 amino acid ABC transporter substrate-binding protein -
  Q7618_RS02975 (Q7618_02965) - 581002..581607 (+) 606 WP_000670162.1 nitroreductase family protein -
  Q7618_RS02980 (Q7618_02970) pepV 581620..583020 (+) 1401 WP_000560281.1 dipeptidase PepV -
  Q7618_RS02985 (Q7618_02975) - 583074..583652 (+) 579 WP_000078149.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 70361.85 Da        Isoelectric Point: 9.2208

>NTDB_id=791987 Q7618_RS02960 WP_001061170.1 577182..579026(+) (uvrC) [Streptococcus pneumoniae strain 2006C08-243]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPSIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSL
TKIKEASVDEIVEVGVPRAVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=791987 Q7618_RS02960 WP_001061170.1 577182..579026(+) (uvrC) [Streptococcus pneumoniae strain 2006C08-243]
ATGAACAACTTGATTAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTCATAAGGATAAAAATGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAATCGAGTACGGTCCTATTTTCGTGGAAGTCATGATACCAAGACAG
AGGCTCTGGTGTCTGAAATTGTGGATTTTGAATTTATTGTTACGGAGTCTAATATTGAGGCACTTCTCCTAGAAATCAAC
CTGATCAAGGAAAACAAGCCCAAGTACAATATCATGCTCAAGGATGACAAGTCCTATCCTTCCATCAAAATCACCAATGA
GCGCTATCCACGCTTGATTATCACTCGTCAGGTCAAAAAGGACGGAGGTCTTTATTTTGGACCCTATCCCGATGTGGGGG
CAGCCAATGAAATCAAGCGGTTGCTGGATCGGATATTCCCTTTTCGTAAGTGTACCAACCCGCCCTCTAAGGTCTGTTTT
TATTACCATATCGGTCAATGCATGGCCCACACCATCTGTAAGAAGGATGAGACTTATTTCAAGTCTATGGCCCAGGAGGT
TTCTGATTTTCTGAAAGGGCAGGATAACAAAATCATTGATGAGCTAAAGGGCAAAATGGCAGCGGCAGCCCAGACTATGG
AGTTTGAACGTGCGGCGGAATACCGTGACCTGATTCAGGCTATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCTAAG
GATCTCCAAAATCGCGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAGGG
TAAGCTCATCGAGCGCGATGTCAATCTCTTCCCCTACTTCAATGATCCAGATGAGGATTTTTTGACCTATGTAGGACAAT
TCTATCAAGAAAAATCTCACCTAGTTCCCAATGAGGTACTGATTCCGCAGGATATTGACGAAGAAGCTGTCAAGGCTTTG
GTGGATACCAAGATTCTCAAACCCCAACGTGGAGAGAAAAAACAGCTGGTCAATCTAGCCATAAAAAATGCACGTGTTAG
TCTGGAGCAGAAATTTAACCTGCTAGAGAAATCTGTCGAGAAGACCCAAGGAGCTATTGAAAATCTAGGACGTTTGCTCC
AAATCCCGACCCCAGTACGTATCGAGTCCTTCGATAACTCTAATATCATGGGAACTAGCCCTGTTTCGGCTATGGTGGTC
TTTGTCAACGGTAAACCGAGTAAGAAGGATTACCGCAAGTACAAGATAAAAACGGTTGTTGGACCAGACGACTATGCCAG
CATGAGAGAGGTCATTCGCAGACGCTATGGTCGAGTACAGCGTGAGGCTTTGACTCCTCCAGATTTGATTGTGATTGATG
GGGGGCAAGGTCAAGTCAATATCGCTAAGCAGGTTATCCAAGAGGAACTGGGCTTGGATATTCCAATTGCTGGGCTGCAA
AAGAATGATAAGCACCAAACCCATGAACTGCTCTTTGGAGATCCGCTTGAGGTGGTGGACTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATCCAAGATGAGGTGCACCGCTTTGCCATTACCTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTCTCATCTCAATTGGATGGGATTGATGGTCTGGGACCTAAACGCAAGCAAAATCTCATGAGGCACTTCAAGTCTCTG
ACCAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGAGTACCAAGAGCAGTAGCAGAGGCTGTGCAAAGAAA
GTTGAACCCGCAGGGAGAAGCCTTGCCTCAAGTAGCAGAAGAAAGAGTAGATTACCAAACGGAAGGAAACCACAATGAAC
CATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(197-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

98.371

100

0.984
  uvrC Streptococcus pneumoniae R6

98.208

100

0.982
  uvrC Streptococcus pneumoniae D39

98.208

100

0.982