Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   QMM27_RS07065 Genome accession   NZ_AP025939
Coordinates   1417767..1418444 (-) Length   225 a.a.
NCBI ID   WP_000548957.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Utah_35B-24     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1412767..1423444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMM27_RS07040 (Utah35B_13990) - 1412940..1413569 (-) 630 Protein_1399 NAD(P)-dependent oxidoreductase -
  QMM27_RS07045 - 1413808..1414171 (+) 364 Protein_1400 hypothetical protein -
  QMM27_RS10405 (Utah35B_14000) - 1414427..1414750 (+) 324 Protein_1401 MazG-like protein -
  QMM27_RS07055 (Utah35B_14010) thrS 1414808..1416751 (+) 1944 WP_000608349.1 threonine--tRNA ligase -
  QMM27_RS07060 (Utah35B_14020) - 1416800..1417774 (-) 975 WP_000887969.1 HAMP domain-containing histidine kinase -
  QMM27_RS07065 (Utah35B_14030) braR 1417767..1418444 (-) 678 WP_000548957.1 response regulator transcription factor Regulator
  QMM27_RS07070 (Utah35B_14040) - 1418600..1419673 (+) 1074 WP_001273825.1 DUF2974 domain-containing protein -
  QMM27_RS07075 (Utah35B_14050) - 1419764..1420066 (-) 303 WP_000281594.1 hypothetical protein -
  QMM27_RS07080 (Utah35B_14060) - 1420135..1420572 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  QMM27_RS07085 (Utah35B_14070) - 1420648..1421490 (-) 843 WP_000160943.1 metallophosphoesterase family protein -
  QMM27_RS07090 (Utah35B_14080) - 1421602..1422252 (+) 651 WP_000188512.1 metal-dependent transcriptional regulator -
  QMM27_RS07095 (Utah35B_14090) - 1422433..1423080 (+) 648 WP_000260177.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=79181 QMM27_RS07065 WP_000548957.1 1417767..1418444(-) (braR) [Streptococcus pneumoniae strain Utah_35B-24]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSIFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=79181 QMM27_RS07065 WP_000548957.1 1417767..1418444(-) (braR) [Streptococcus pneumoniae strain Utah_35B-24]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTATATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGCCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGAGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment