Detailed information NTG0791805

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: PVK54_RS05540
• Genome accession: NZ_CP118312
• Coordinates: 1040250..1041086 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 20181688
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1035250..1046086

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PVK54_RS05510 (PVK54_05470)	-	1035666..1036172 (+)	507	WP_397610624.1	hypothetical protein	-
PVK54_RS05515 (PVK54_05475)	-	1036222..1037133 (-)	912	WP_002989777.1	diacylglycerol kinase family protein	-
PVK54_RS05520 (PVK54_05480)	-	1037250..1037900 (-)	651	WP_002984629.1	hemolysin III family protein	-
PVK54_RS05525 (PVK54_05485)	-	1037897..1038337 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
PVK54_RS05530 (PVK54_05490)	ylqF	1038556..1039404 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
PVK54_RS05535 (PVK54_05495)	-	1039394..1040185 (+)	792	WP_002989771.1	ribonuclease HII	-
PVK54_RS05540 (PVK54_05500)	dprA	1040250..1041086 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
PVK54_RS05545 (PVK54_05505)	topA	1041193..1043322 (+)	2130	WP_002989768.1	type I DNA topoisomerase	-
PVK54_RS05550 (PVK54_05510)	-	1043397..1044254 (-)	858	Protein_1048	LysR family transcriptional regulator	-
PVK54_RS05555 (PVK54_05515)	-	1044294..1044860 (+)	567	Protein_1049	PTS sugar transporter subunit IIC	-
PVK54_RS05560 (PVK54_05520)	-	1044875..1045867 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=791805 PVK54_RS05540 WP_002989770.1 1040250..1041086(+) (dprA) [Streptococcus pyogenes strain 20181688]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=791805 PVK54_RS05540 WP_002989770.1 1040250..1041086(+) (dprA) [Streptococcus pyogenes strain 20181688]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367