Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   Q7621_RS05430 Genome accession   NZ_CP131712
Coordinates   1112612..1113961 (-) Length   449 a.a.
NCBI ID   WP_000886210.1    Uniprot ID   Q8DPL8
Organism   Streptococcus pneumoniae strain 2008C09-280     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1107612..1118961
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7621_RS05400 (Q7621_05395) - 1107735..1108721 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  Q7621_RS05405 (Q7621_05400) - 1108969..1109742 (-) 774 WP_000731139.1 ion channel -
  Q7621_RS05410 (Q7621_05405) - 1109789..1110043 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE/ParE family toxin -
  Q7621_RS05415 (Q7621_05410) - 1110045..1110287 (-) 243 WP_000208080.1 DUF6290 family protein -
  Q7621_RS05420 (Q7621_05415) - 1110482..1111738 (+) 1257 WP_000436237.1 ISL3-like element IS1167A family transposase -
  Q7621_RS05425 (Q7621_05420) vicX 1111801..1112610 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  Q7621_RS05430 (Q7621_05425) micB 1112612..1113961 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  Q7621_RS05435 (Q7621_05430) yycF 1113954..1114658 (-) 705 WP_000722076.1 response regulator YycF -
  Q7621_RS05440 (Q7621_05435) mutY 1114713..1115888 (-) 1176 Protein_1074 A/G-specific adenine glycosylase -
  Q7621_RS05445 (Q7621_05440) - 1115985..1116110 (+) 126 WP_001818232.1 hypothetical protein -
  Q7621_RS05450 (Q7621_05445) - 1116216..1117886 (-) 1671 WP_000845292.1 formate--tetrahydrofolate ligase -
  Q7621_RS05455 (Q7621_05450) coaB 1118116..1118805 (+) 690 WP_000699492.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51712.42 Da        Isoelectric Point: 4.9706

>NTDB_id=791647 Q7621_RS05430 WP_000886210.1 1112612..1113961(-) (micB) [Streptococcus pneumoniae strain 2008C09-280]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=791647 Q7621_RS05430 WP_000886210.1 1112612..1113961(-) (micB) [Streptococcus pneumoniae strain 2008C09-280]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAAAATAGACGTGATAATATTCAGTTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGGCTAAATAGTATTCTGTTTTATATGACAGATGGGGT
TCTTGCGACCAACCGTCGGGGTCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGTTGGTTAAGGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAAACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGTGAATATTTGAACCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGCGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGGGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTTTCTCTTGATGAGACCAACCGTATGATGCGCATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCTACCAGTCACCTAGATGTGGAACTGATTAACTTCACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGTTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCACGGTTTGGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGCAAGGGTTCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterProScan.

PAS fold (PAS)

(98-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DPL8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

99.777

100

0.998
  vicK Streptococcus mutans UA159

69.9

89.532

0.626