Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   Q7622_RS02010 Genome accession   NZ_CP131711
Coordinates   380157..380789 (+) Length   210 a.a.
NCBI ID   WP_000698433.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 2014C08-275     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 375157..385789
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7622_RS01985 (Q7622_01980) mvaD 375434..376387 (+) 954 WP_000373456.1 diphosphomevalonate decarboxylase -
  Q7622_RS01990 (Q7622_01985) - 376374..377381 (+) 1008 WP_000562377.1 phosphomevalonate kinase -
  Q7622_RS01995 (Q7622_01990) fni 377365..378375 (+) 1011 WP_000210628.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  Q7622_RS02000 (Q7622_01995) liaF 378453..379151 (+) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  Q7622_RS02005 (Q7622_02000) - 379148..380143 (+) 996 WP_000743662.1 sensor histidine kinase -
  Q7622_RS02010 (Q7622_02005) vraR 380157..380789 (+) 633 WP_000698433.1 response regulator transcription factor Regulator
  Q7622_RS02015 (Q7622_02010) - 380790..381032 (+) 243 Protein_394 DNA alkylation repair protein -
  Q7622_RS02020 (Q7622_02015) - 380957..381559 (+) 603 Protein_395 DNA alkylation repair protein -
  Q7622_RS02025 (Q7622_02020) - 382018..382620 (+) 603 Protein_396 serine protease -
  Q7622_RS02030 (Q7622_02025) - 382922..383281 (+) 360 WP_000378123.1 tyrosine-type recombinase/integrase -
  Q7622_RS02035 (Q7622_02030) tig 383475..384758 (+) 1284 WP_000116462.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23539.00 Da        Isoelectric Point: 4.5739

>NTDB_id=791496 Q7622_RS02010 WP_000698433.1 380157..380789(+) (vraR) [Streptococcus pneumoniae strain 2014C08-275]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=791496 Q7622_RS02010 WP_000698433.1 380157..380789(+) (vraR) [Streptococcus pneumoniae strain 2014C08-275]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGATGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41