Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QMM27_RS01740 Genome accession   NZ_AP025939
Coordinates   338651..339283 (+) Length   210 a.a.
NCBI ID   WP_000698432.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Utah_35B-24     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 333651..344283
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMM27_RS01715 (Utah35B_03290) mvaD 333928..334881 (+) 954 WP_000373475.1 diphosphomevalonate decarboxylase -
  QMM27_RS01720 (Utah35B_03300) - 334868..335875 (+) 1008 WP_000562442.1 phosphomevalonate kinase -
  QMM27_RS01725 (Utah35B_03310) fni 335859..336869 (+) 1011 WP_000210623.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  QMM27_RS01730 (Utah35B_03320) liaF 336947..337645 (+) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  QMM27_RS01735 (Utah35B_03330) - 337642..338637 (+) 996 WP_000743661.1 sensor histidine kinase -
  QMM27_RS01740 (Utah35B_03340) vraR 338651..339283 (+) 633 WP_000698432.1 response regulator transcription factor Regulator
  QMM27_RS01745 (Utah35B_03350) - 339284..339526 (+) 243 WP_001820556.1 DNA alkylation repair protein -
  QMM27_RS01750 (Utah35B_03360) - 339508..339762 (+) 255 WP_000729868.1 DNA alkylation repair protein -
  QMM27_RS01755 - 339839..339934 (+) 96 Protein_343 DNA alkylation repair protein -
  QMM27_RS01760 (Utah35B_03370) - 340393..340995 (+) 603 Protein_344 serine protease -
  QMM27_RS01765 (Utah35B_03380) - 341297..341656 (+) 360 WP_000378120.1 tyrosine-type recombinase/integrase -
  QMM27_RS01770 (Utah35B_03390) - 342010..342963 (+) 954 WP_001155321.1 IS30-like element ISSpn8 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23562.04 Da        Isoelectric Point: 4.6491

>NTDB_id=79132 QMM27_RS01740 WP_000698432.1 338651..339283(+) (vraR) [Streptococcus pneumoniae strain Utah_35B-24]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=79132 QMM27_RS01740 WP_000698432.1 338651..339283(+) (vraR) [Streptococcus pneumoniae strain Utah_35B-24]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTTAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTCGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment