Detailed information NTG0791307

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: Q7624_RS07505
• Genome accession: NZ_CP131709
• Coordinates: 1471453..1472130 (-)
• Length: 225 a.a.
• NCBI ID: WP_000548959.1
• Uniprot ID: Q9S1K2
• Organism: Streptococcus pneumoniae strain 2016S11-245
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1466453..1477130

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q7624_RS07475 (Q7624_07450)	-	1466616..1467245 (-)	630	WP_000762091.1	NAD(P)-dependent oxidoreductase	-
Q7624_RS07480 (Q7624_07455)	-	1467483..1467683 (+)	201	WP_001814296.1	hypothetical protein	-
Q7624_RS07485 (Q7624_07460)	-	1468113..1468253 (+)	141	WP_000422775.1	MazG-like protein	-
Q7624_RS07490 (Q7624_07465)	-	1468260..1468436 (+)	177	WP_000166031.1	MazG-like protein	-
Q7624_RS07495 (Q7624_07470)	thrS	1468494..1470437 (+)	1944	WP_000608349.1	threonine--tRNA ligase	-
Q7624_RS07500 (Q7624_07475)	-	1470486..1471460 (-)	975	WP_000887953.1	HAMP domain-containing histidine kinase	-
Q7624_RS07505 (Q7624_07480)	braR	1471453..1472130 (-)	678	WP_000548959.1	response regulator transcription factor	Regulator
Q7624_RS07510 (Q7624_07485)	-	1472286..1473359 (+)	1074	WP_001273823.1	DUF2974 domain-containing protein	-
Q7624_RS07515 (Q7624_07490)	-	1473450..1473752 (-)	303	WP_000281609.1	hypothetical protein	-
Q7624_RS07520 (Q7624_07495)	-	1473820..1474257 (-)	438	WP_001166785.1	Rrf2 family transcriptional regulator	-
Q7624_RS07525 (Q7624_07500)	-	1474333..1475175 (-)	843	WP_000160938.1	metallophosphoesterase family protein	-
Q7624_RS07530 (Q7624_07505)	-	1475287..1475937 (+)	651	WP_000188505.1	metal-dependent transcriptional regulator	-
Q7624_RS07535	-	1475918..1476109 (+)	192	WP_001816503.1	hypothetical protein	-
Q7624_RS07540 (Q7624_07510)	-	1476135..1476810 (+)	676	Protein_1491	nicotinamide mononucleotide transporter	-
Q7624_RS07545 (Q7624_07520)	-	1476912..1477025 (+)	114	Protein_1492	glutamine ABC transporter permease	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25964.16 Da
• Isoelectric Point: 5.1362

>NTDB_id=791307 Q7624_RS07505 WP_000548959.1 1471453..1472130(-) (braR) [Streptococcus pneumoniae strain 2016S11-245]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide

• Length: 678 bp

>NTDB_id=791307 Q7624_RS07505 WP_000548959.1 1471453..1472130(-) (braR) [Streptococcus pneumoniae strain 2016S11-245]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-221)

3D structure

• AlphaFold DB: Q9S1K2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	48.624	96.889	0.471
vicR	Streptococcus mutans UA159	35.319	100	0.369