Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   Q7626_RS07530 Genome accession   NZ_CP131707
Coordinates   1489952..1490629 (-) Length   225 a.a.
NCBI ID   WP_000548961.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 2018C08-270     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1484952..1495629
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7626_RS07505 (Q7626_07500) - 1485125..1485754 (-) 630 WP_000762091.1 NAD(P)-dependent oxidoreductase -
  Q7626_RS07510 (Q7626_07505) - 1485992..1486355 (+) 364 Protein_1485 hypothetical protein -
  Q7626_RS07515 - 1486612..1486935 (+) 324 Protein_1486 MazG-like protein -
  Q7626_RS07520 (Q7626_07515) thrS 1486993..1488936 (+) 1944 WP_000608330.1 threonine--tRNA ligase -
  Q7626_RS07525 (Q7626_07520) - 1488985..1489959 (-) 975 WP_000887972.1 HAMP domain-containing histidine kinase -
  Q7626_RS07530 (Q7626_07525) braR 1489952..1490629 (-) 678 WP_000548961.1 response regulator transcription factor Regulator
  Q7626_RS07535 (Q7626_07530) - 1490785..1491858 (+) 1074 WP_001273825.1 DUF2974 domain-containing protein -
  Q7626_RS07540 (Q7626_07535) - 1491949..1492251 (-) 303 WP_000281608.1 hypothetical protein -
  Q7626_RS07545 (Q7626_07540) - 1492319..1492756 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  Q7626_RS07550 (Q7626_07545) - 1492832..1493674 (-) 843 WP_000160958.1 metallophosphoesterase family protein -
  Q7626_RS07555 (Q7626_07550) - 1493786..1494436 (+) 651 WP_000188504.1 metal-dependent transcriptional regulator -
  Q7626_RS07560 (Q7626_07555) - 1494613..1495290 (+) 678 WP_000260179.1 nicotinamide mononucleotide transporter family protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25950.13 Da        Isoelectric Point: 5.1362

>NTDB_id=791075 Q7626_RS07530 WP_000548961.1 1489952..1490629(-) (braR) [Streptococcus pneumoniae strain 2018C08-270]
MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=791075 Q7626_RS07530 WP_000548961.1 1489952..1490629(-) (braR) [Streptococcus pneumoniae strain 2018C08-270]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTTTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

34.894

100

0.364