Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   Q7626_RS02745 Genome accession   NZ_CP131707
Coordinates   550518..552365 (+) Length   615 a.a.
NCBI ID   WP_001061136.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 2018C08-270     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 545518..557365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7626_RS02725 (Q7626_02720) - 546350..547129 (+) 780 WP_000290025.1 alpha/beta hydrolase family protein -
  Q7626_RS02730 (Q7626_02725) murM 547241..548461 (+) 1221 WP_001816673.1 peptidoglycan bridge formation alanyltransferase MurM -
  Q7626_RS02735 (Q7626_02730) murN 548466..549698 (+) 1233 WP_001229519.1 peptidoglycan bridge formation alanyltransferase MurN -
  Q7626_RS02740 (Q7626_02735) - 549777..550478 (+) 702 WP_001267410.1 M57 family metalloprotease -
  Q7626_RS02745 (Q7626_02740) uvrC 550518..552365 (+) 1848 WP_001061136.1 excinuclease ABC subunit UvrC Machinery gene
  Q7626_RS02750 (Q7626_02745) - 552355..553188 (+) 834 WP_024477575.1 metallophosphoesterase family protein -
  Q7626_RS02755 (Q7626_02750) - 553370..554170 (-) 801 WP_000714615.1 amino acid ABC transporter substrate-binding protein -
  Q7626_RS02760 (Q7626_02755) - 554341..554946 (+) 606 WP_000670162.1 nitroreductase family protein -
  Q7626_RS02765 (Q7626_02760) pepV 554959..556359 (+) 1401 WP_000560280.1 dipeptidase PepV -
  Q7626_RS02770 (Q7626_02765) - 556413..556991 (+) 579 WP_000078149.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 615 a.a.        Molecular weight: 70553.17 Da        Isoelectric Point: 9.2183

>NTDB_id=791040 Q7626_RS02745 WP_001061136.1 550518..552365(+) (uvrC) [Streptococcus pneumoniae strain 2018C08-270]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDSKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSL
TKIKEASVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP

Nucleotide


Download         Length: 1848 bp        

>NTDB_id=791040 Q7626_RS02745 WP_001061136.1 550518..552365(+) (uvrC) [Streptococcus pneumoniae strain 2018C08-270]
ATGAACAACTTGATTAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTCATAAGGATAAAAATGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAATCGAGTACGGTCCTATTTTCGTGGAAGTCATGATACCAAGACAG
AGGCTCTGGTGTCTGAAATTGTGGATTTTGAATTTATCGTCACTGAGTCCAATATTGAGGCGCTTCTGCTGGAAATCAAC
CTGATCAAGGAAAATAAGCCCAAGTACAATATCATGCTCAAGGATGATAAGTCTTATCCTTTTATCAAAATCACCAATGA
GCGCTATCCACGGCTTATCATTACTCGTCAGGTCAAAAAGGACGGTGGTCTTTATTTTGGCCCTTATCCAGATGTGGGGG
CAGCCAATGAAATCAAGCGACTTCTAGATAGGATTTTCCCTTTTCGAAAATGTACCAACCCGCCCTCTAAGGTCTGTTTT
TATTACCATATCGGCCAGTGTATGGCCCACACCATCTGTAAGAAGGATGAGGCTTATTTCAAGTCTATGGCCCAGGAGGT
TTCTGATTTTCTGAAAGGGCAGGATAACAAAATCATTGATGAGCTAAAGGGCAAAATGGCAGCGGCAGCCCAGACTATGG
AGTTTGAACGTGCGGCGGAATACCGTGACCTGATTCAGGCTATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCTAAG
GATCTCCAAAATCGCGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTTCGTCAGGG
CAAGCTCATCGAGCGCGATGTCAATCTCTTCCCCTACTTCAATGATCCAGATGAGGATTTCTTGACCTATGTGGGACAAT
TCTATCAAGAAAAATCTCACCTAGTTCCCAATGAGGTACTGATTCCGCAGGATATTGACGAAGAGGCTGTCAAGGCCTTG
GTGGATTCCAAGATTCTTAAGCCTCAACGTGGAGAGAAAAAGCAGCTGGTCAATTTAGCTATAAAAAATGCCCGTGTTAG
CCTAGAGCAGAAGTTCAACCTGCTAGAGAAATCTGTCGAGAAGACCCAAGGAGCTATTGAAAATCTAGGACGCTTGCTTC
AAATCCCAACCCCAGTTCGCATCGAGTCCTTCGATAACTCCAACATCATGGGAACTAGTCCTGTTTCAGCCATGGTGGTC
TTTGTCAACGGCAAGCCTAGTAAGAAGGATTACCGTAAGTATAAAATCAAGACCGTAGTCGGGCCAGACGACTATGCCAG
TATGCGAGAGGTCATTCGCAGACGCTATGGTCGAGTACAGCGTGAGGCTTTGACTCCTCCAGATTTGATTGTGATTGATG
GGGGGCAAGGTCAAGTCAATATTGCTAAGCAAGTCATCCAAGAAGAACTGGGCTTGGATATTCCAATTGCAGGTCTGCAA
AAGAATGATAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTGGAAGTGGTGGACTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATCCAAGATGAGGTGCACCGCTTTGCCATCACCTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTCTCATCTCAATTGGATGGGATTGATGGTCTGGGACCTAAACGCAAGCAAAATCTCATGAGGCACTTCAAGTCTCTG
ACCAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGAGTACCAAGAGCAGTAGCAGAGGCTGTGCAAACCAA
GTTGAACCCGCAGGAAACAGAAATCTTGCTTCAAGTGGCGGAAGAAAGAGTAGATTACCAAACGGAAGGAAACCACAATA
AACCATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(197-228)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

97.886

100

0.979
  uvrC Streptococcus pneumoniae TIGR4

97.886

100

0.979
  uvrC Streptococcus pneumoniae D39

97.886

100

0.979