Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   Q7627_RS07735 Genome accession   NZ_CP131706
Coordinates   1514725..1515402 (-) Length   225 a.a.
NCBI ID   WP_000548991.1    Uniprot ID   A0A501PEF7
Organism   Streptococcus pneumoniae strain 2018N21-288     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1509725..1520402
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7627_RS07710 (Q7627_07695) - 1509898..1510526 (-) 629 Protein_1525 NAD(P)-dependent oxidoreductase -
  Q7627_RS07715 (Q7627_07700) - 1510765..1511128 (+) 364 Protein_1526 hypothetical protein -
  Q7627_RS07720 (Q7627_07705) - 1511385..1511708 (+) 324 WP_000422776.1 MazG-like protein -
  Q7627_RS07725 (Q7627_07710) thrS 1511766..1513709 (+) 1944 WP_000608349.1 threonine--tRNA ligase -
  Q7627_RS07730 (Q7627_07715) - 1513758..1514732 (-) 975 WP_000887969.1 HAMP domain-containing histidine kinase -
  Q7627_RS07735 (Q7627_07720) braR 1514725..1515402 (-) 678 WP_000548991.1 response regulator transcription factor Regulator
  Q7627_RS07740 (Q7627_07725) - 1515558..1516631 (+) 1074 WP_001273835.1 DUF2974 domain-containing protein -
  Q7627_RS07745 (Q7627_07730) - 1516773..1517024 (-) 252 WP_001810245.1 hypothetical protein -
  Q7627_RS07750 (Q7627_07735) - 1517092..1517529 (-) 438 WP_001166791.1 Rrf2 family transcriptional regulator -
  Q7627_RS07755 (Q7627_07740) - 1517605..1518447 (-) 843 WP_000160934.1 metallophosphoesterase family protein -
  Q7627_RS07760 (Q7627_07745) - 1518559..1519209 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  Q7627_RS07765 (Q7627_07750) dtd 1519826..1520269 (-) 444 WP_000691400.1 D-aminoacyl-tRNA deacylase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25936.11 Da        Isoelectric Point: 5.1362

>NTDB_id=790959 Q7627_RS07735 WP_000548991.1 1514725..1515402(-) (braR) [Streptococcus pneumoniae strain 2018N21-288]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=790959 Q7627_RS07735 WP_000548991.1 1514725..1515402(-) (braR) [Streptococcus pneumoniae strain 2018N21-288]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAACGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGAGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A501PEF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369