Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QMM10_RS01935 Genome accession   NZ_AP025938
Coordinates   374159..374791 (+) Length   210 a.a.
NCBI ID   WP_000698432.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701057     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 369159..379791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMM10_RS01910 (PC1044_03630) mvaD 369436..370389 (+) 954 WP_000373461.1 diphosphomevalonate decarboxylase -
  QMM10_RS01915 (PC1044_03640) - 370376..371383 (+) 1008 WP_044727650.1 phosphomevalonate kinase -
  QMM10_RS01920 (PC1044_03650) fni 371367..372377 (+) 1011 WP_044727651.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  QMM10_RS01925 (PC1044_03660) liaF 372455..373153 (+) 699 WP_044727652.1 cell wall-active antibiotics response protein LiaF -
  QMM10_RS01930 (PC1044_03670) - 373150..374145 (+) 996 WP_044727653.1 sensor histidine kinase -
  QMM10_RS01935 (PC1044_03680) vraR 374159..374791 (+) 633 WP_000698432.1 response regulator transcription factor Regulator
  QMM10_RS01940 (PC1044_03690) - 374792..375034 (+) 243 WP_001820556.1 DNA alkylation repair protein -
  QMM10_RS01945 (PC1044_03700) - 375016..375270 (+) 255 WP_000729868.1 DNA alkylation repair protein -
  QMM10_RS10570 - 375289..375442 (+) 154 Protein_383 DNA alkylation repair protein -
  QMM10_RS01955 (PC1044_03710) - 375901..376503 (+) 603 Protein_384 serine protease -
  QMM10_RS01960 (PC1044_03720) - 376805..377197 (+) 393 WP_000378121.1 tyrosine-type recombinase/integrase -
  QMM10_RS01965 (PC1044_03730) tig 377358..378641 (+) 1284 WP_000116472.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23562.04 Da        Isoelectric Point: 4.6491

>NTDB_id=79011 QMM10_RS01935 WP_000698432.1 374159..374791(+) (vraR) [Streptococcus pneumoniae strain PZ900701057]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=79011 QMM10_RS01935 WP_000698432.1 374159..374791(+) (vraR) [Streptococcus pneumoniae strain PZ900701057]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGACGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTTAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTCGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment