Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PUW49_RS10480 Genome accession   NZ_CP118054
Coordinates   2046909..2048180 (-) Length   423 a.a.
NCBI ID   WP_070242126.1    Uniprot ID   A0A413KPH7
Organism   Streptococcus anginosus strain VSI37     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2041909..2053180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW49_RS10440 (PUW49_10440) - 2042623..2042934 (-) 312 WP_003027765.1 DUF1292 domain-containing protein -
  PUW49_RS10445 (PUW49_10445) ruvX 2042952..2043371 (-) 420 WP_003031265.1 Holliday junction resolvase RuvX -
  PUW49_RS10450 (PUW49_10450) - 2043371..2043637 (-) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  PUW49_RS10455 (PUW49_10455) - 2043918..2044055 (-) 138 WP_024053217.1 hypothetical protein -
  PUW49_RS10460 (PUW49_10460) - 2044083..2044475 (-) 393 WP_024053218.1 SP0191 family lipoprotein -
  PUW49_RS10465 (PUW49_10465) - 2044579..2045148 (-) 570 WP_024053219.1 SP0191 family lipoprotein -
  PUW49_RS10470 (PUW49_10470) spx 2045234..2045632 (-) 399 WP_003026638.1 transcriptional regulator Spx -
  PUW49_RS10475 (PUW49_10475) recA 2045719..2046864 (-) 1146 WP_003026640.1 recombinase RecA Machinery gene
  PUW49_RS10480 (PUW49_10480) cinA 2046909..2048180 (-) 1272 WP_070242126.1 competence/damage-inducible protein A Machinery gene
  PUW49_RS10485 (PUW49_10485) - 2048781..2049200 (+) 420 Protein_2029 EamA family transporter -
  PUW49_RS10490 (PUW49_10490) - 2049303..2049881 (-) 579 WP_070242127.1 DNA-3-methyladenine glycosylase I -
  PUW49_RS10495 (PUW49_10495) ruvA 2049892..2050482 (-) 591 WP_003026647.1 Holliday junction branch migration protein RuvA -
  PUW49_RS10500 (PUW49_10500) - 2050644..2051087 (+) 444 WP_024053224.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45703.21 Da        Isoelectric Point: 6.3701

>NTDB_id=789694 PUW49_RS10480 WP_070242126.1 2046909..2048180(-) (cinA) [Streptococcus anginosus strain VSI37]
MKAEIIAVGTEILTGQIVNTNARFLSEKLASLGVDVYFQTAVGDNEARLLSILEIARNRSNLVILTGGLGPTEDDLTKQT
LAKFLNRRLVFDRMATEKLDCFFASRPDYARTPNNDRQAQIVEGSTPLQNETGLAVGGVIEVGGVTYVVLPGPPSELKPM
VNNELVPLLATGQKLYSRVLRFFGIGESQLVTLLGDLIDNQTDPTIAPYAKTGEVTLRLSTKAASQNEADIKFAHLEKKI
LSVQTFEKQHLADLFYTYGDDNSLGQTAFELLRRAGKTVTAAESLTAGLFQATLSNFAGASNVFSGGFVTYSMEEKSRML
GIPLADLEKHGVVSAFTAEKMAEQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATTGDVQSIKVNIAGRSRTDVR
KIAVLHAFNLLRKTLLKNENMLQ

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=789694 PUW49_RS10480 WP_070242126.1 2046909..2048180(-) (cinA) [Streptococcus anginosus strain VSI37]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAAATTCTGACAGGTCAGATTGTCAATACAAATGCCCGATTTTTATCGGA
AAAATTAGCGAGTCTGGGTGTAGATGTGTATTTCCAAACAGCGGTTGGAGATAATGAAGCTCGTCTGTTATCCATTTTAG
AAATTGCTCGAAATCGTAGTAATTTGGTCATCTTAACTGGAGGATTAGGCCCAACAGAAGATGACTTGACTAAGCAAACT
TTGGCAAAATTCTTAAATCGTAGGTTGGTATTTGACCGAATGGCTACGGAGAAATTGGACTGCTTTTTCGCAAGTCGACC
GGATTATGCTCGAACACCAAACAATGATCGGCAAGCTCAGATAGTGGAAGGATCGACTCCTCTCCAAAACGAAACCGGAC
TTGCGGTGGGAGGCGTGATTGAAGTCGGTGGCGTGACTTATGTTGTTCTCCCCGGACCGCCTAGTGAATTAAAGCCTATG
GTAAATAATGAGCTGGTTCCGCTGTTAGCAACTGGTCAAAAATTGTATTCAAGAGTCTTGCGATTCTTTGGTATCGGTGA
AAGTCAATTAGTAACCCTTTTAGGAGATTTAATTGATAATCAGACCGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AGGTGACATTGCGATTGTCCACCAAGGCTGCTAGTCAAAATGAAGCAGATATTAAGTTTGCCCATTTAGAAAAGAAAATT
TTATCTGTACAGACTTTTGAGAAACAACATTTAGCAGATCTTTTCTATACTTATGGAGATGATAATTCTCTGGGACAAAC
AGCTTTTGAACTGTTGAGAAGAGCAGGAAAGACCGTCACAGCAGCTGAAAGTTTGACTGCAGGACTCTTTCAAGCAACTT
TGTCAAACTTTGCTGGAGCCTCCAATGTTTTTAGTGGTGGATTTGTTACCTACAGTATGGAGGAAAAGAGCCGAATGCTG
GGCATTCCCTTGGCAGACTTAGAAAAGCATGGGGTAGTTTCAGCTTTTACAGCGGAGAAAATGGCTGAGCAGGCAAGAAA
ATTGACCGCTAGTGACTATGCGGTGAGCTTGACAGGTGTGGCAGGTCCAGACAGCTTAGAAGGACATCCAGCAGGGACAG
TTTATATCGGTTTAGCAACCACAGGGGATGTTCAGTCTATTAAGGTTAATATTGCCGGTCGCAGTCGGACAGATGTACGT
AAAATAGCCGTTCTGCATGCTTTCAATCTGCTACGAAAAACTTTATTAAAAAACGAAAATATGCTACAATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A413KPH7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

76.316

98.818

0.754
  cinA Streptococcus mitis NCTC 12261

75.359

98.818

0.745
  cinA Streptococcus pneumoniae TIGR4

75.12

98.818

0.742
  cinA Streptococcus pneumoniae Rx1

75.12

98.818

0.742
  cinA Streptococcus pneumoniae R6

75.12

98.818

0.742
  cinA Streptococcus pneumoniae D39

74.88

98.818

0.74
  cinA Streptococcus mutans UA159

72.104

100

0.721
  cinA Streptococcus suis isolate S10

55.288

98.345

0.544
  cinA Bacillus subtilis subsp. subtilis str. 168

45.933

98.818

0.454