Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   PUW49_RS08730 Genome accession   NZ_CP118054
Coordinates   1724266..1724955 (-) Length   229 a.a.
NCBI ID   WP_024052511.1    Uniprot ID   A0A412PLG4
Organism   Streptococcus anginosus strain VSI37     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1719266..1729955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW49_RS08710 (PUW49_08710) nrdR 1719751..1720224 (-) 474 WP_024052506.1 transcriptional regulator NrdR -
  PUW49_RS08715 (PUW49_08715) - 1720390..1720986 (+) 597 Protein_1692 hypothetical protein -
  PUW49_RS08720 (PUW49_08720) - 1721034..1721849 (-) 816 WP_024052509.1 endonuclease/exonuclease/phosphatase family protein -
  PUW49_RS08725 (PUW49_08725) - 1721866..1724055 (-) 2190 WP_042754091.1 PTS transporter subunit IIBC -
  PUW49_RS08730 (PUW49_08730) covR 1724266..1724955 (-) 690 WP_024052511.1 response regulator transcription factor Regulator
  PUW49_RS08735 (PUW49_08735) gndA 1724964..1726388 (-) 1425 WP_024052512.1 NADP-dependent phosphogluconate dehydrogenase -
  PUW49_RS08740 (PUW49_08740) - 1726686..1727309 (-) 624 WP_024052513.1 DNA alkylation repair protein -
  PUW49_RS08745 (PUW49_08745) - 1727360..1727896 (-) 537 WP_070811379.1 YceD family protein -
  PUW49_RS08750 (PUW49_08750) - 1728009..1728864 (+) 856 Protein_1699 XRE family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26430.47 Da        Isoelectric Point: 6.2732

>NTDB_id=789680 PUW49_RS08730 WP_024052511.1 1724266..1724955(-) (covR) [Streptococcus anginosus strain VSI37]
MGKRILLVEKEKKLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTEFAAQLSVIKPASVIIVL
DNRDNILQYTEEIQRFAVAYMVEPFIVTDLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKIDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=789680 PUW49_RS08730 WP_024052511.1 1724266..1724955(-) (covR) [Streptococcus anginosus strain VSI37]
ATGGGGAAGCGGATTTTATTAGTTGAGAAAGAAAAAAAATTAGCGCAATTTATTGGCTTAGAGCTACAAAAAGAAGGTTA
TCGAGTTGATCTTTTTGAAACAGGAAAAGATGCTTTGGCGTCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGAATTTGCCGCACAATTAAGTGTGATAAAGCCTGCTTCGGTCATCATTGTATTG
GATAATCGTGATAATATTCTTCAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GACGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGGCGTGATTTTATTGACCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
AGAGAGTATGATTTATTAGCAACATTGATGGGAAGTCATCAGGCTTTAAGCCGTGAACAGTTGTTAGAACGCGTGTGGAA
ATACGAAGGAGCTGTTGAAACAAATGTTGTCGATGTTTATATTCGCTATCTTCGTAGTAAAATTGATATAGCGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A412PLG4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.614

99.563

0.454