Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   PUW71_RS02220 Genome accession   NZ_CP118053
Coordinates   422760..423815 (+) Length   351 a.a.
NCBI ID   WP_024052081.1    Uniprot ID   A0A413KQY5
Organism   Streptococcus anginosus strain VSI40     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 417760..428815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW71_RS02190 (PUW71_02190) - 418281..418916 (-) 636 WP_024052085.1 YigZ family protein -
  PUW71_RS02195 (PUW71_02195) comFA/cflA 418973..420274 (+) 1302 WP_024052084.1 DEAD/DEAH box helicase Machinery gene
  PUW71_RS02200 (PUW71_02200) comFC/cflB 420271..420936 (+) 666 WP_024052083.1 ComF family protein Machinery gene
  PUW71_RS02205 (PUW71_02205) raiA 421014..421556 (+) 543 WP_003025754.1 ribosome-associated translation inhibitor RaiA -
  PUW71_RS02210 (PUW71_02210) rsmD 421744..422292 (+) 549 WP_171021853.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  PUW71_RS02215 (PUW71_02215) coaD 422282..422779 (+) 498 WP_021001374.1 pantetheine-phosphate adenylyltransferase -
  PUW71_RS02220 (PUW71_02220) sepM 422760..423815 (+) 1056 WP_024052081.1 SepM family pheromone-processing serine protease Regulator
  PUW71_RS02225 (PUW71_02225) - 423954..424517 (+) 564 WP_024052080.1 YutD-like domain-containing protein -
  PUW71_RS02230 (PUW71_02230) rlmN 424558..425640 (+) 1083 WP_024052079.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  PUW71_RS02235 (PUW71_02235) - 425633..426163 (+) 531 WP_024052078.1 VanZ family protein -
  PUW71_RS02240 (PUW71_02240) trpB 426524..427732 (+) 1209 Protein_399 tryptophan synthase subunit beta -
  PUW71_RS02245 (PUW71_02245) cclA/cilC 427893..428552 (-) 660 WP_024052075.1 A24 family peptidase Machinery gene

Sequence

Protein


Download         Length: 351 a.a.        Molecular weight: 38290.25 Da        Isoelectric Point: 10.1906

>NTDB_id=789594 PUW71_RS02220 WP_024052081.1 422760..423815(+) (sepM) [Streptococcus anginosus strain VSI40]
MEKPRNKFKKWPIIAVVGVILLFLSFVVPLPYYIEVPGGAADVRQVLRVDNKEDKEKGSYNFVTVGIQHATLAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDITLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKELIDYVGAQKIGSKVKVNYVEDGQKKSATGKIIKLENGKNGIGISLIDRTEVTSNTPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEVKKSNPKAKTNYETAL
AAAKKIKTKMKIVPVKTLQDAIDYLKSTKKS

Nucleotide


Download         Length: 1056 bp        

>NTDB_id=789594 PUW71_RS02220 WP_024052081.1 422760..423815(+) (sepM) [Streptococcus anginosus strain VSI40]
ATGGAAAAACCAAGAAATAAATTTAAAAAATGGCCGATAATTGCAGTAGTAGGGGTGATTTTGCTTTTCTTATCTTTTGT
AGTTCCCTTGCCTTATTATATTGAGGTGCCAGGTGGTGCAGCGGATGTCCGTCAGGTATTGCGCGTGGACAACAAAGAAG
ATAAGGAAAAAGGTTCTTATAATTTTGTAACGGTTGGAATTCAGCATGCGACCCTCGCTCATTTGGTTTATGCTTGGCTG
ACACCTTTTACGGATATTTATTCGGCGAAGGATTTGACTGGTGGAACTTCTGATAAAGAATACATGCGGATCAATCAGTT
TTATATGGAAACGTCGCAAAACCTAGCTAAATACCAAGGGTTGAAAAAAGCTGGCAAAGACATTACTCTGAAATATCTAG
GGGTTTACGTCTTGCAAGTCACAAAGAATTCTACTTTTAAAGGTATTTTAAATATTGCAGATACCGTGACAGGTGTGAAT
GATAAGACTTTCAATAGTTCAAAAGAATTGATAGACTATGTCGGAGCGCAAAAGATTGGCAGCAAGGTCAAGGTGAACTA
TGTAGAAGACGGTCAGAAGAAGTCTGCTACAGGTAAAATTATTAAACTTGAAAATGGGAAAAACGGGATTGGCATTAGTT
TGATTGACCGAACAGAAGTCACAAGCAACACACCAATTGAATTTTCAACTGCCGGTATTGGTGGACCAAGTGCGGGCTTG
ATGTTTAGTTTGGCAATTTATACGCAAATTGCAGATCCAACATTGAGAGACGGCAGAAATATTGCTGGGACAGGTTCGAT
TGACCGAGAAGGAAAAGTTGGCGACATTGGTGGGATTGACAAAAAAGTTGTTTCAGCAGCTAAAAATGGCGCAGAAATTT
TCTTTGCGCCAAATAATCCAGTCACCAAGGAAGTGAAAAAATCCAATCCTAAAGCGAAAACAAACTATGAGACAGCTTTG
GCAGCTGCTAAAAAAATTAAAACTAAAATGAAAATTGTACCTGTCAAGACCTTGCAAGACGCAATTGATTACCTCAAGAG
CACAAAAAAGTCGTAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(234-307)

PDZ domain (PDZ_2)

(133-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A413KQY5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

64.223

97.151

0.624