Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   PUW62_RS08155 Genome accession   NZ_CP118046
Coordinates   1620614..1621303 (-) Length   229 a.a.
NCBI ID   WP_024052511.1    Uniprot ID   A0A412PLG4
Organism   Streptococcus anginosus strain VSI52     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1615614..1626303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW62_RS08135 (PUW62_08135) nrdR 1616099..1616572 (-) 474 WP_024052506.1 transcriptional regulator NrdR -
  PUW62_RS08140 (PUW62_08140) - 1616738..1617334 (+) 597 Protein_1571 hypothetical protein -
  PUW62_RS08145 (PUW62_08145) - 1617382..1618197 (-) 816 WP_024052509.1 endonuclease/exonuclease/phosphatase family protein -
  PUW62_RS08150 (PUW62_08150) - 1618214..1620403 (-) 2190 WP_042754091.1 PTS transporter subunit IIBC -
  PUW62_RS08155 (PUW62_08155) covR 1620614..1621303 (-) 690 WP_024052511.1 response regulator transcription factor Regulator
  PUW62_RS08160 (PUW62_08160) gndA 1621312..1622736 (-) 1425 WP_024052512.1 NADP-dependent phosphogluconate dehydrogenase -
  PUW62_RS08165 (PUW62_08165) - 1623034..1623657 (-) 624 WP_024052513.1 DNA alkylation repair protein -
  PUW62_RS08170 (PUW62_08170) - 1623708..1624244 (-) 537 WP_024052514.1 YceD family protein -
  PUW62_RS08175 (PUW62_08175) - 1624357..1625213 (+) 857 Protein_1578 XRE family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26430.47 Da        Isoelectric Point: 6.2732

>NTDB_id=789484 PUW62_RS08155 WP_024052511.1 1620614..1621303(-) (covR) [Streptococcus anginosus strain VSI52]
MGKRILLVEKEKKLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTEFAAQLSVIKPASVIIVL
DNRDNILQYTEEIQRFAVAYMVEPFIVTDLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKIDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=789484 PUW62_RS08155 WP_024052511.1 1620614..1621303(-) (covR) [Streptococcus anginosus strain VSI52]
ATGGGGAAGCGGATTTTATTAGTTGAGAAAGAAAAAAAATTAGCGCAATTTATTGGCTTAGAGCTACAAAAAGAAGGTTA
TCGAGTTGATCTTTTTGAAACAGGAAAAGATGCTTTGGCGTCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGAATTTGCCGCACAATTAAGTGTGATAAAGCCTGCTTCGGTCATCATTGTATTG
GATAATCGTGATAATATTCTTCAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GACGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGGCGTGATTTTATTGACCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
AGAGAGTATGATTTATTAGCAACATTGATGGGAAGTCATCAGGCTTTAAGCCGTGAACAGTTGTTAGAACGCGTGTGGAA
ATACGAAGGAGCTGTTGAAACAAATGTTGTCGATGTTTATATTCGCTATCTTCGTAGTAAAATTGATATAGCGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A412PLG4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.614

99.563

0.454