Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   PUW62_RS04020 Genome accession   NZ_CP118046
Coordinates   819867..821219 (+) Length   450 a.a.
NCBI ID   WP_003032751.1    Uniprot ID   A0A2I1UXL3
Organism   Streptococcus anginosus strain VSI52     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 814867..826219
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW62_RS03995 (PUW62_03995) ccpA 815114..816118 (+) 1005 WP_024051861.1 catabolite control protein A Regulator
  PUW62_RS04000 (PUW62_04000) - 816211..817209 (+) 999 WP_024051860.1 glycosyltransferase -
  PUW62_RS04005 (PUW62_04005) - 817211..818524 (+) 1314 WP_024051859.1 glycosyltransferase family 4 protein -
  PUW62_RS04010 (PUW62_04010) - 818551..818892 (+) 342 WP_024051858.1 hypothetical protein -
  PUW62_RS04015 (PUW62_04015) micA 819173..819874 (+) 702 WP_003025150.1 response regulator YycF Regulator
  PUW62_RS04020 (PUW62_04020) micB 819867..821219 (+) 1353 WP_003032751.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PUW62_RS04025 (PUW62_04025) vicX 821221..822024 (+) 804 WP_024051857.1 MBL fold metallo-hydrolase Regulator
  PUW62_RS04030 (PUW62_04030) - 822103..822372 (+) 270 Protein_756 YbaN family protein -
  PUW62_RS04035 (PUW62_04035) rnc 822753..823451 (+) 699 WP_003025140.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51376.62 Da        Isoelectric Point: 4.6876

>NTDB_id=789474 PUW62_RS04020 WP_003032751.1 819867..821219(+) (micB) [Streptococcus anginosus strain VSI52]
MIDNIRQFIVSKDFVFVLLILGFILVITLLSLENRRDNIRIRQLNQKVKDLIAGNYSEILDVQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDIEDEYDLRDLITKVPE
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTDTQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=789474 PUW62_RS04020 WP_003032751.1 819867..821219(+) (micB) [Streptococcus anginosus strain VSI52]
ATGATTGATAATATTAGACAATTTATTGTATCAAAAGACTTTGTATTTGTTTTACTTATTTTAGGGTTCATCTTGGTGAT
TACCTTGCTTTCCTTGGAAAATAGGCGAGACAATATTCGTATTCGCCAATTGAATCAAAAAGTAAAAGATTTAATTGCAG
GCAATTACTCAGAAATTTTAGATGTACAAGGTGGTCCAGAAATTACGGATATTACCAATAGTATCAATGATTTATCTGAG
GTAATCCGTCTAACGCATGAAAATTTAGAGCAAGAAACTAAGCGCCTGTCGAGTATTTTATCCTATATGACGGACGGTGT
TCTTGCGACCAATCGTCGTGGGCAGATTATCATGATCAATGATATGGCAACCAAGCAGTTGGGGGTCAAAGAGTCTGAAG
CACGAAAGATGAATATCTTAAAACTGTTGGATATCGAAGACGAATATGACTTACGAGACTTGATTACGAAAGTTCCAGAG
TTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTCCGATTTGCCTTGATTCGGCGAGAATCAGG
CTTTATTTCAGGGCTGGTTGCAGTGCTACACGATACAACGGAGCAGGAAAAAGAAGAGCGTGAGCGGAGACTGTTTGTTT
CGAATGTCAGTCACGAATTACGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCACTAGATGAAGGTGCCTTATCA
GAACCAGTCGCACCGGATTTCATCAAGGTTTCATTAGACGAGACCAATCGGATGATGCGCATGGTTTCGGACTTGCTGAG
TTTGTCACGTATTGACAATGCAACCAGTCATTTGGATATTGAATTGACGAATTTTACTGCTTTTATCACCTTTATTTTGA
ACCGTTTTGATAAAATCAGAAGCCAGAATGATGATAAAAAGTATGAAATTATACGAGATTATCCGATTAACTCTATTTGG
GTCGAAATTGATACAGATAAGATGACACAGGTGATTGATAATATTATCAACAATGCCATTAAATATTCTCCTGACGGTGG
CAAGATTACGGTCAGTATGAAAACGACGGATACCCAAATGATTTTGTCGATTTCAGATGAAGGCTTAGGAATTCCTAAAA
AAGATTTACCGAAAATTTTTGATAGATTTTATCGTGTAGATAAAGCGAGAAGTCGTGCACAAGGTGGGTCCGGACTGGGC
TTAGCCATTGCCAAAGAGATTATCAAGCAGCATAACGGCTTTATCTGGGCAAAGAGCGAGTACGGCAAAGGTTCAACCTT
TACTATTGTCCTGCCTTATGATAAGGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I1UXL3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

81.093

97.556

0.791
  vicK Streptococcus mutans UA159

71.883

90.889

0.653