Detailed information NTG0078844

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: QML87_RS08855
• Genome accession: NZ_AP025936
• Coordinates: 1750377..1751276 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904867.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700617
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1745377..1756276

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QML87_RS08835 (PC0607_17390)	rsmA	1746131..1747003 (-)	873	WP_001216869.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
QML87_RS08840 (PC0607_17400)	-	1747134..1747442 (-)	309	WP_000333257.1	hypothetical protein	-
QML87_RS08845 (PC0607_17410)	-	1747435..1748076 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
QML87_RS08850 (PC0607_17420)	-	1748078..1750108 (-)	2031	WP_000825281.1	bacteriocin-associated integral membrane family protein	-
QML87_RS08855 (PC0607_17430)	comR	1750377..1751276 (-)	900	WP_000904867.1	helix-turn-helix domain-containing protein	Regulator
QML87_RS08860 (PC0607_17440)	rnmV	1751348..1751908 (-)	561	WP_000664448.1	ribonuclease M5	-
QML87_RS08865 (PC0607_17450)	-	1751908..1752681 (-)	774	WP_000575607.1	TatD family hydrolase	-
QML87_RS08870 (PC0607_17460)	-	1752987..1753676 (-)	690	WP_230738454.1	DUF1542 domain-containing protein	-
QML87_RS08875 (PC0607_17470)	rpmH	1753915..1754049 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
QML87_RS08880 (PC0607_17480)	-	1754194..1755408 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
QML87_RS08885 (PC0607_17490)	-	1755564..1755857 (-)	294	WP_000977365.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35191.04 Da
• Isoelectric Point: 5.0703

>NTDB_id=78844 QML87_RS08855 WP_000904867.1 1750377..1751276(-) (comR) [Streptococcus pneumoniae strain PZ900700617]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=78844 QML87_RS08855 WP_000904867.1 1750377..1751276(-) (comR) [Streptococcus pneumoniae strain PZ900700617]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (7-59)

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368