Detailed information NTG0787685

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: PT256_RS05725
• Genome accession: NZ_CP117817
• Coordinates: 1232898..1234226 (+)
• Length: 442 a.a.
• NCBI ID: WP_061784235.1
• Uniprot ID: -
• Organism: Legionella pneumophila strain D5573
• Function: regulate pilin expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1234540..1237196	1232898..1234226	flank	314

Gene organization within MGE regions

Location: 1232898..1237196

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PT256_RS05725 (PT256_05725)	pilR	1232898..1234226 (+)	1329	WP_061784235.1	sigma-54 dependent transcriptional regulator	Regulator
PT256_RS05730 (PT256_05730)	-	1234540..1235289 (-)	750	WP_080450748.1	IS5 family transposase	-
PT256_RS05735 (PT256_05735)	-	1235524..1235769 (+)	246	WP_011213531.1	hypothetical protein	-
PT256_RS05740 (PT256_05740)	-	1236171..1237196 (+)	1026	WP_226997379.1	IS4 family transposase	-

Sequence

Protein

• Length: 442 a.a.
• Molecular weight: 49270.26 Da
• Isoelectric Point: 6.9042

>NTDB_id=787685 PT256_RS05725 WP_061784235.1 1232898..1234226(+) (pilR) [Legionella pneumophila strain D5573]
MTKSKVLVIDDEPDIRELLTLTLSRMGLTCDAVSDFKQGVEHIKQNYYSLVLTDMRLPDGDGIEIVKFIQKYKPQMPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPIDLKMLRDLVKTALSMQNPPTEKPDEDLLVGESLVMQQLRENIHKLARSQAPVFI
QGASGVGKELVAQLIHVNGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEVPVDVRILSASHKNLIEEVNAGAFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
RKLSKNQNRNLVKINPSCFEILSRYHFPGNVRELENILERAMAMCEGEVIEPSDLHLPRTTITPGVAVPSTSTNLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

Nucleotide

• Length: 1329 bp

>NTDB_id=787685 PT256_RS05725 WP_061784235.1 1232898..1234226(+) (pilR) [Legionella pneumophila strain D5573]
ATGACCAAAAGTAAAGTGCTTGTTATAGATGACGAACCAGATATAAGAGAGTTATTAACTCTTACTTTATCACGTATGGG
TTTAACTTGCGATGCAGTGTCTGACTTTAAGCAAGGCGTAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ATATGCGTTTACCTGATGGAGATGGTATAGAAATTGTTAAATTCATTCAGAAATACAAACCGCAGATGCCAGTTGCCGTC
ATTACTGCCTATGGAAATGTCGAGGGTGCGGTCAACACTTTAAAGGCGGGTGCATTTGATTACGTATCAAAACCTATAGA
CTTAAAAATGCTTAGAGATCTCGTTAAGACGGCATTATCCATGCAAAACCCGCCTACCGAGAAGCCTGATGAAGATCTAC
TGGTTGGTGAAAGTTTGGTAATGCAACAACTTCGTGAAAACATTCATAAATTAGCTCGCAGTCAGGCACCAGTTTTTATT
CAAGGAGCTTCAGGTGTTGGAAAAGAATTGGTCGCTCAGTTGATCCATGTTAATGGTCCCAGAAAGGATAAGCCATTTAT
TCCTGTAAACTGTGGCGCAATACCTGGTGAGTTGATGGAATCAGAGTTTTTTGGCCATAAAAAAGGGAGCTTTACAGGAG
CGATTTCTGATAAAACAGGGTTGTTTGTTGCGGCTCATGGTGGCACTTTGTTTCTTGATGAAATCGCCGAACTTCCTCTC
GCCATGCAGGTAAAATTGCTACGTGCCATTCAGGAGAAGGCAATTAAGCCGATAGGTGAGTTATATGAAGTTCCTGTGGA
TGTTCGCATCCTAAGTGCGAGTCATAAAAATTTGATTGAGGAAGTTAATGCAGGGGCATTTCGTCAAGATTTGTATTATC
GAATTAATGTGATTGAATTGCGTGTCCCAACTTTAATGGAAAGGCTTTCAGATATTCCTTGCCTGACAGAGGCGATATTA
AGAAAGTTATCTAAAAATCAAAACAGAAACCTGGTGAAAATAAATCCATCCTGTTTTGAAATATTGAGTCGTTATCATTT
TCCAGGAAATGTCAGAGAACTGGAGAATATCCTCGAGCGTGCCATGGCTATGTGTGAAGGAGAGGTTATAGAACCATCCG
ATTTACATTTGCCAAGAACAACAATAACCCCAGGTGTTGCCGTACCCTCCACGTCAACTAACTTAAATGGTTACCTTCAG
GATCAGGAAAAAGAGTTAATTCTTGATGCGCTTGAGAAAACAAAATGGAACAGAACCGCTGCTGCACAACTACTGGGGGT
CAGCTTCCGAACTCTCCGTTATCGATTAAAAAAACTGGGCCTTGATTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (6-115)

• Bacterial regulatory protein, Fis family (HTH_8) (399-439)

• Sigma-54 interaction domain (Sigma54_activat) (134-300)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	59.551	100	0.6
pilR	Acinetobacter baumannii strain A118	48.584	100	0.505