Detailed information NTG0787644

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: PT258_RS05635
• Genome accession: NZ_CP117814
• Coordinates: 1270319..1271647 (+)
• Length: 442 a.a.
• NCBI ID: WP_061784235.1
• Uniprot ID: -
• Organism: Legionella pneumophila strain D5241
• Function: regulate pilin expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1271961..1274617	1270319..1271647	flank	314

Gene organization within MGE regions

Location: 1270319..1274617

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PT258_RS05635 (PT258_05635)	pilR	1270319..1271647 (+)	1329	WP_061784235.1	sigma-54 dependent transcriptional regulator	Regulator
PT258_RS05640 (PT258_05640)	-	1271961..1272710 (-)	750	WP_080450748.1	IS5 family transposase	-
PT258_RS05645 (PT258_05645)	-	1272945..1273190 (+)	246	WP_011213531.1	hypothetical protein	-
PT258_RS05650 (PT258_05650)	-	1273592..1274617 (+)	1026	WP_226997379.1	IS4 family transposase	-

Sequence

Protein

• Length: 442 a.a.
• Molecular weight: 49270.26 Da
• Isoelectric Point: 6.9042

>NTDB_id=787644 PT258_RS05635 WP_061784235.1 1270319..1271647(+) (pilR) [Legionella pneumophila strain D5241]
MTKSKVLVIDDEPDIRELLTLTLSRMGLTCDAVSDFKQGVEHIKQNYYSLVLTDMRLPDGDGIEIVKFIQKYKPQMPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPIDLKMLRDLVKTALSMQNPPTEKPDEDLLVGESLVMQQLRENIHKLARSQAPVFI
QGASGVGKELVAQLIHVNGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEVPVDVRILSASHKNLIEEVNAGAFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
RKLSKNQNRNLVKINPSCFEILSRYHFPGNVRELENILERAMAMCEGEVIEPSDLHLPRTTITPGVAVPSTSTNLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

Nucleotide

• Length: 1329 bp

>NTDB_id=787644 PT258_RS05635 WP_061784235.1 1270319..1271647(+) (pilR) [Legionella pneumophila strain D5241]
ATGACCAAAAGTAAAGTGCTTGTTATAGATGACGAACCAGATATAAGAGAGTTATTAACTCTTACTTTATCACGTATGGG
TTTAACTTGCGATGCAGTGTCTGACTTTAAGCAAGGCGTAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ATATGCGTTTACCTGATGGAGATGGTATAGAAATTGTTAAATTCATTCAGAAATACAAACCGCAGATGCCAGTTGCCGTC
ATTACTGCCTATGGAAATGTCGAGGGTGCGGTCAACACTTTAAAGGCGGGTGCATTTGATTACGTATCAAAACCTATAGA
CTTAAAAATGCTTAGAGATCTCGTTAAGACGGCATTATCCATGCAAAACCCGCCTACCGAGAAGCCTGATGAAGATCTAC
TGGTTGGTGAAAGTTTGGTAATGCAACAACTTCGTGAAAACATTCATAAATTAGCTCGCAGTCAGGCACCAGTTTTTATT
CAAGGAGCTTCAGGTGTTGGAAAAGAATTGGTCGCTCAGTTGATCCATGTTAATGGTCCCAGAAAGGATAAGCCATTTAT
TCCTGTAAACTGTGGCGCAATACCTGGTGAGTTGATGGAATCAGAGTTTTTTGGCCATAAAAAAGGGAGCTTTACAGGAG
CGATTTCTGATAAAACAGGGTTGTTTGTTGCGGCTCATGGTGGCACTTTGTTTCTTGATGAAATCGCCGAACTTCCTCTC
GCCATGCAGGTAAAATTGCTACGTGCCATTCAGGAGAAGGCAATTAAGCCGATAGGTGAGTTATATGAAGTTCCTGTGGA
TGTTCGCATCCTAAGTGCGAGTCATAAAAATTTGATTGAGGAAGTTAATGCAGGGGCATTTCGTCAAGATTTGTATTATC
GAATTAATGTGATTGAATTGCGTGTCCCAACTTTAATGGAAAGGCTTTCAGATATTCCTTGCCTGACAGAGGCGATATTA
AGAAAGTTATCTAAAAATCAAAACAGAAACCTGGTGAAAATAAATCCATCCTGTTTTGAAATATTGAGTCGTTATCATTT
TCCAGGAAATGTCAGAGAACTGGAGAATATCCTCGAGCGTGCCATGGCTATGTGTGAAGGAGAGGTTATAGAACCATCCG
ATTTACATTTGCCAAGAACAACAATAACCCCAGGTGTTGCCGTACCCTCCACGTCAACTAACTTAAATGGTTACCTTCAG
GATCAGGAAAAAGAGTTAATTCTTGATGCGCTTGAGAAAACAAAATGGAACAGAACCGCTGCTGCACAACTACTGGGGGT
CAGCTTCCGAACTCTCCGTTATCGATTAAAAAAACTGGGCCTTGATTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (6-115)

• Bacterial regulatory protein, Fis family (HTH_8) (399-439)

• Sigma-54 interaction domain (Sigma54_activat) (134-300)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	59.551	100	0.6
pilR	Acinetobacter baumannii strain A118	48.584	100	0.505