Detailed information NTG0786549

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: Q3Y68_RS16570
• Genome accession: NZ_CP130681
• Coordinates: 3761882..3763006 (+)
• Length: 374 a.a.
• NCBI ID: WP_030404779.1
• Uniprot ID: A0A6B3QRH4
• Organism: Streptomyces sp. HUAS CX7
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3756882..3768006

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q3Y68_RS16560 (Q3Y68_16560)	-	3758053..3759843 (-)	1791	WP_233646018.1	hypothetical protein	-
Q3Y68_RS16565 (Q3Y68_16565)	radA/sms	3760391..3761800 (+)	1410	WP_102932190.1	DNA repair protein RadA	Machinery gene
Q3Y68_RS16570 (Q3Y68_16570)	disA	3761882..3763006 (+)	1125	WP_030404779.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
Q3Y68_RS16575 (Q3Y68_16575)	-	3763026..3763868 (-)	843	WP_233646019.1	hypothetical protein	-
Q3Y68_RS16580 (Q3Y68_16580)	-	3764027..3764953 (+)	927	WP_125629511.1	A/G-specific adenine glycosylase	-
Q3Y68_RS16585 (Q3Y68_16585)	-	3765252..3765785 (+)	534	WP_003975479.1	SigE family RNA polymerase sigma factor	-
Q3Y68_RS16590 (Q3Y68_16590)	-	3765773..3766450 (+)	678	WP_176154385.1	hypothetical protein	-
Q3Y68_RS16595 (Q3Y68_16595)	cseB	3766574..3767278 (+)	705	WP_233646020.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40084.82 Da
• Isoelectric Point: 5.0058

>NTDB_id=786549 Q3Y68_RS16570 WP_030404779.1 3761882..3763006(+) (disA) [Streptomyces sp. HUAS CX7]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTSLRDGLERVLRGNTGGLIVLGSDKTVEQMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=786549 Q3Y68_RS16570 WP_030404779.1 3761882..3763006(+) (disA) [Streptomyces sp. HUAS CX7]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCGCCCGGCACGTCCCTGCGCGACGGCCTGGAGCGGGTCCTGCGCGGCAACACCGGCGGTCTGATCGTGC
TGGGCTCCGACAAGACCGTCGAGCAGATGTGCACGGGCGGTTTCGTGCTGGACGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGTCGTCCGACCTGTCGAAGATCCTGCGGGCCGGGGTGCAGCTCCTTCC
GGATCCCACCATTCCGACGGAGGAGACCGGTACGCGGCATCGGACCGCCGACCGGGTCAGCAAGCAGGTCGGCTTCCCCG
TGGTGTCGGTTTCGCAGTCGATGCGGCTGATCGCGTTGTACGTGGACGGGCAGCGGCGGGTGCTGGAGGACTCGGCGGCG
ATCCTGTCGCGGGCCAATCAGGCACTGGCGACGCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTCTCCGCGGTCGCGCAGCGGCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGGCGGCTGCTCGCACTGCAGTTGGACGAGCTGATCGCC
GGGGTGGAGCCCGAACGCGAGCTGGTCGTGCGGGACTACGTGCCGGAGCCGACCGCCAAGCGCTCCCGTACGGTCGACGA
GGCACTCGCCGAGCTGGACAAGCTCAGCCACGCGGAACTGCTGGAACTGTCGACCGTGGCCCGGGCCCTGGGCTACACCG
GGTCGCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGGCTGCTGGCCAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGTCTGCAGAAGCTGCTCGCCGCCAGTGTCGACGACCTGCAGACCGTGGA
CGGCGTCGGCGAGGCGCGGGCGCGCAGCGTGCGCGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

3D structure

• AlphaFold DB: A0A6B3QRH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.26	96.524	0.447