Detailed information NTG0078587

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: LLL8_RS11875
• Genome accession: NZ_AP025700
• Coordinates: 2387860..2390382 (-)
• Length: 840 a.a.
• NCBI ID: WP_251899988.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain L8
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2382860..2395382

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLL8_RS11855 (LLL8_23170)	ruvB	2383120..2384121 (-)	1002	WP_003131994.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
LLL8_RS11860 (LLL8_23180)	ruvA	2384248..2384841 (-)	594	WP_003131995.1	Holliday junction branch migration protein RuvA	Machinery gene
LLL8_RS11865 (LLL8_23190)	hexB	2384951..2386921 (-)	1971	WP_032947013.1	DNA mismatch repair endonuclease MutL	Machinery gene
LLL8_RS11870 (LLL8_23200)	-	2387050..2387745 (-)	696	WP_012898700.1	hypothetical protein	-
LLL8_RS11875 (LLL8_23210)	hexA	2387860..2390382 (-)	2523	WP_251899988.1	DNA mismatch repair protein MutS	Machinery gene
LLL8_RS11880 (LLL8_23220)	-	2390576..2390923 (-)	348	WP_012898702.1	RicAFT regulatory complex protein RicA family protein	-
LLL8_RS11885 (LLL8_23230)	-	2391140..2392021 (-)	882	WP_058203820.1	NAD(P)-dependent oxidoreductase	-
LLL8_RS11890 (LLL8_23240)	-	2392063..2392269 (-)	207	WP_003132002.1	hypothetical protein	-
LLL8_RS11900 (LLL8_23250)	-	2392564..2392941 (-)	378	WP_003132003.1	DUF1634 domain-containing protein	-
LLL8_RS11905 (LLL8_23260)	-	2392941..2393792 (-)	852	WP_021463283.1	sulfite exporter TauE/SafE family protein	-
LLL8_RS11910 (LLL8_23270)	-	2393978..2394157 (+)	180	WP_003132007.1	hypothetical protein	-

Sequence

Protein

• Length: 840 a.a.
• Molecular weight: 94217.16 Da
• Isoelectric Point: 4.6171

>NTDB_id=78587 LLL8_RS11875 WP_251899988.1 2387860..2390382(-) (hexA) [Lactococcus lactis strain L8]
MAEKISPGMQQYLDIKQDYPDAFLLFRMGDFYELFYDDAVNAAQILELTLTSRNKNSENPIPMAGVPHHAAAEYIDKLVD
LGYKVAVAEQMEDPKKAVGIVKRAVTQVITPGTTIDTANSVDNNFLVAIDFKDKHYALSYMDLSTGEFKVTELSEFSAVV
GEIASLKAREIVAGFTLDESQLKVFERQMNLLISEQIEIPENLLIDLSGLTALENQVASKLLAYVKETQMRDLSHLQEVE
HYEIKDFLQMDFATKSSLELTANKRENKKHGTLYWLLDETKTAMGTRMLRSWIDRPLVSNSAIQKRMEIVQIFLDHFFER
SDLIEALKGVYDLERLASCVSFGKAVPVDFLQLANSLSNVPAIKNILGMLNEAPLEELKSQLDEIPELSDLINSAISENA
SRTITEGGIIKKGYNAQLDKYREALENGTSWIAKLEADEKAKTGISTLRIDYNRKDGYYFHITQSQLNSVPEHFYRKATL
KNSERFGSQELTEIEEIMLEAREKSSSLEYDLFMGLRTETEQYIGRLQALAKTIAEIDCLQSLSVVAEKQGYIRPTLTDG
SRIVEIKGGRHAVVEAVMGAQEYVPNDIELPEQTDIQLITGPNMSGKSTYMRQFALTVIMAQIGSFVPAETANLPIFDAI
FTRIGASDNLISGESTFMVEMSEANHAIQKASSRSLIIFDELGRGTATYDGMALAQAIIEYVHDHIGAKTLFATHYHELT
DLDEALDHLDNVHVATLEQNGNVTFLHKITEGPADKSYGIHVAKIAGLPQPLLERADLILQKLENKPLPAKKVADEQEQL
SLFDFTENSSEIIEMIKRQNVDNMTAREALNFLWELKDSL

Nucleotide

• Length: 2523 bp

>NTDB_id=78587 LLL8_RS11875 WP_251899988.1 2387860..2390382(-) (hexA) [Lactococcus lactis strain L8]
ATGGCTGAAAAAATTTCACCAGGAATGCAACAATATTTAGACATCAAACAAGATTATCCCGATGCTTTCTTGCTCTTTCG
GATGGGTGATTTTTATGAGCTTTTCTATGATGATGCAGTGAATGCTGCCCAAATATTAGAATTAACCCTGACTTCAAGAA
ATAAAAATTCAGAAAATCCAATTCCAATGGCTGGTGTTCCCCACCATGCAGCAGCTGAATACATTGATAAATTGGTTGAT
TTAGGCTACAAAGTGGCTGTTGCTGAACAAATGGAAGACCCGAAAAAAGCGGTCGGAATTGTTAAACGGGCAGTAACACA
GGTGATTACCCCAGGGACAACGATTGACACTGCAAATTCGGTTGATAATAATTTCTTGGTGGCAATTGACTTCAAAGATA
AACATTATGCTCTTTCCTATATGGACTTATCAACTGGGGAATTCAAGGTGACAGAGCTCAGCGAATTTTCAGCGGTAGTA
GGAGAAATTGCTTCACTCAAGGCGCGGGAAATTGTAGCTGGTTTTACTTTAGATGAAAGTCAGTTAAAAGTTTTTGAAAG
ACAAATGAATCTTTTGATTTCAGAACAAATTGAAATTCCTGAAAATTTACTGATAGATTTGTCAGGATTGACCGCCTTAG
AAAATCAAGTCGCTTCAAAATTGTTGGCTTATGTCAAAGAAACACAAATGCGTGATTTGAGTCACTTACAAGAAGTTGAA
CATTATGAAATTAAAGACTTTTTGCAAATGGACTTTGCGACAAAATCATCTTTAGAGCTGACGGCAAATAAAAGAGAAAA
TAAAAAACATGGCACACTTTATTGGTTGCTTGATGAGACGAAAACAGCGATGGGAACCAGAATGTTACGGTCGTGGATTG
ACCGTCCTTTGGTTTCAAATTCAGCCATTCAAAAACGAATGGAAATTGTTCAAATTTTCTTAGACCATTTCTTTGAGCGT
TCCGATTTGATAGAAGCCTTAAAAGGGGTCTATGATTTAGAACGTTTGGCTTCATGTGTTTCTTTTGGTAAGGCTGTTCC
GGTTGATTTTTTGCAGCTGGCTAATTCTTTATCAAATGTTCCTGCTATCAAAAATATTTTGGGAATGCTTAATGAAGCTC
CATTAGAAGAGTTAAAAAGCCAATTAGACGAAATTCCAGAATTATCTGATTTAATTAATTCAGCTATTAGTGAGAATGCC
TCAAGAACGATTACTGAAGGGGGCATTATTAAAAAAGGCTACAATGCTCAATTGGATAAATATCGGGAGGCGCTTGAAAA
TGGGACTTCTTGGATTGCAAAATTGGAAGCAGATGAAAAAGCCAAGACAGGAATTTCCACACTGCGAATTGATTATAATC
GTAAGGATGGTTATTATTTTCATATTACTCAAAGTCAGTTGAATAGTGTTCCTGAACATTTTTATCGGAAGGCAACTTTG
AAAAATTCTGAGCGTTTTGGTTCTCAGGAATTAACTGAAATTGAAGAAATTATGTTGGAAGCGCGTGAAAAATCATCATC
TCTAGAATATGATTTATTCATGGGCCTTCGGACTGAAACGGAGCAATATATTGGCAGACTACAAGCTCTAGCCAAAACAA
TTGCTGAAATTGACTGTTTACAAAGTCTATCTGTCGTTGCCGAAAAACAAGGATATATCCGTCCGACGCTTACAGACGGC
TCAAGAATTGTTGAAATTAAAGGCGGTCGTCATGCGGTCGTTGAAGCGGTCATGGGTGCTCAAGAATATGTGCCAAATGA
TATTGAACTGCCTGAACAAACAGATATTCAACTCATCACAGGACCGAATATGTCAGGTAAATCAACCTACATGCGTCAAT
TTGCTTTGACGGTGATTATGGCTCAAATTGGATCTTTTGTTCCAGCAGAAACAGCCAATTTACCAATTTTTGATGCCATC
TTTACACGGATTGGTGCCAGTGATAACTTGATTTCAGGGGAATCGACCTTTATGGTTGAAATGTCTGAGGCCAATCATGC
CATTCAAAAGGCAAGCAGTCGCAGCCTGATTATTTTTGATGAATTAGGGCGAGGAACGGCAACTTATGATGGGATGGCTC
TAGCTCAAGCAATTATTGAATATGTTCATGACCATATTGGGGCAAAGACCTTGTTTGCTACGCATTATCATGAATTGACA
GACTTAGATGAAGCGCTCGATCATCTTGATAATGTCCATGTTGCTACCTTGGAGCAAAATGGGAATGTGACTTTTTTGCA
TAAAATAACAGAGGGACCAGCTGATAAATCCTATGGGATTCATGTGGCGAAAATTGCAGGTTTACCACAGCCTTTGTTAG
AGCGAGCAGATTTGATTTTGCAGAAGTTAGAAAATAAACCTTTGCCTGCTAAAAAAGTTGCTGATGAACAAGAACAACTT
AGTTTATTTGATTTTACCGAAAATTCTTCAGAAATTATTGAAATGATAAAAAGGCAAAATGTTGATAATATGACTGCAAG
AGAGGCATTGAATTTCTTGTGGGAACTTAAAGATTCACTTTGA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (598-784)

• MutS domain III (MutS_III) (254-544)

• MutS domain II (MutS_II) (124-237)

• MutS domain I (MutS_I) (7-116)

• MutS family domain IV (MutS_IV) (413-503)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	64.455	100	0.648
mutS	Pseudomonas stutzeri strain ATCC 17587	37.69	100	0.385