Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LLL8_RS04605 Genome accession   NZ_AP025700
Coordinates   920076..920705 (+) Length   209 a.a.
NCBI ID   WP_003131402.1    Uniprot ID   Q9CH48
Organism   Lactococcus lactis strain L8     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 915076..925705
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLL8_RS04580 (LLL8_08790) - 915363..916562 (+) 1200 WP_058203638.1 FtsW/RodA/SpoVE family cell cycle protein -
  LLL8_RS04585 (LLL8_08800) - 916593..917891 (+) 1299 WP_058203639.1 LCP family protein -
  LLL8_RS04590 (LLL8_08810) rpsN 917989..918258 (+) 270 WP_010905608.1 30S ribosomal protein S14 -
  LLL8_RS04595 (LLL8_08820) liaF 918424..919053 (+) 630 WP_003131399.1 cell wall-active antibiotics response protein LiaF -
  LLL8_RS04600 (LLL8_08830) - 919050..920048 (+) 999 WP_012897540.1 sensor histidine kinase -
  LLL8_RS04605 (LLL8_08840) vraR 920076..920705 (+) 630 WP_003131402.1 response regulator transcription factor Regulator
  LLL8_RS04610 (LLL8_08850) - 920776..921582 (+) 807 WP_109990770.1 Cof-type HAD-IIB family hydrolase -
  LLL8_RS04615 (LLL8_08860) - 921685..922275 (+) 591 WP_012897543.1 peptidylprolyl isomerase -
  LLL8_RS04620 (LLL8_08870) - 922277..922708 (+) 432 WP_139916468.1 CvfD/Ygs/GSP13 family RNA-binding post-transcriptional regulator -
  LLL8_RS04625 (LLL8_08880) - 922705..923310 (+) 606 WP_003131406.1 TVP38/TMEM64 family protein -
  LLL8_RS04630 (LLL8_08890) - 923532..924776 (+) 1245 WP_251900338.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23204.85 Da        Isoelectric Point: 5.3572

>NTDB_id=78523 LLL8_RS04605 WP_003131402.1 920076..920705(+) (vraR) [Lactococcus lactis strain L8]
MEKIKLLIVDDHQMVRLGLSSFMNIQPDIEVVGEAADGESGFLKTEMLDPDVILMDLVMDRLDGIGATQKILAKNPERKI
LILTSFIDDEKVFPALAAGAKGYILKTSQAADIASAIRKVANGEDVLSDAVKEKIAQQKHRKHELYDDLSKRELEVLKVL
ATGLSNQEIADELFISLKTVKTHVSNIFNKLEVSDRTQATIYAIQHHLV

Nucleotide


Download         Length: 630 bp        

>NTDB_id=78523 LLL8_RS04605 WP_003131402.1 920076..920705(+) (vraR) [Lactococcus lactis strain L8]
ATGGAAAAAATTAAACTTTTAATTGTTGATGACCACCAGATGGTGCGACTAGGTTTATCAAGTTTCATGAATATTCAACC
CGATATCGAAGTGGTTGGTGAAGCTGCCGATGGCGAGTCAGGATTTTTAAAAACTGAAATGCTTGACCCTGATGTTATTC
TCATGGATTTAGTGATGGATCGACTTGATGGAATTGGAGCAACGCAAAAGATTTTAGCCAAAAATCCAGAACGAAAAATT
TTAATTCTAACCAGTTTTATTGATGACGAAAAAGTTTTTCCAGCTTTAGCTGCTGGAGCTAAAGGTTATATTCTTAAAAC
ATCACAAGCCGCTGATATTGCATCTGCAATCAGAAAAGTTGCCAATGGAGAAGATGTCCTTTCCGATGCTGTCAAGGAAA
AGATTGCTCAACAAAAACATCGAAAACATGAATTATATGATGATTTATCAAAAAGAGAATTAGAAGTATTAAAAGTACTT
GCGACGGGACTTTCTAATCAAGAAATTGCAGATGAACTTTTTATCAGTTTAAAAACAGTCAAAACTCATGTTTCTAATAT
TTTTAATAAGCTTGAAGTGTCAGACCGAACTCAAGCAACAATTTATGCCATTCAACATCACTTAGTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-117)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CH48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.565

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.416

Multiple sequence alignment