Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   LLL8_RS02100 Genome accession   NZ_AP025700
Coordinates   418730..420172 (-) Length   480 a.a.
NCBI ID   WP_010905315.1    Uniprot ID   Q9CIG6
Organism   Lactococcus lactis strain L8     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 413730..425172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLL8_RS02075 (LLL8_04020) - 413762..415102 (+) 1341 WP_023188995.1 H2O-forming NADH oxidase -
  LLL8_RS02080 (LLL8_04030) - 415192..415581 (+) 390 WP_010905314.1 single-stranded DNA-binding protein -
  LLL8_RS02085 (LLL8_04040) groES 415701..415985 (+) 285 WP_003131589.1 co-chaperone GroES -
  LLL8_RS02090 (LLL8_04050) groL 416073..417701 (+) 1629 WP_058206244.1 chaperonin GroEL -
  LLL8_RS02095 (LLL8_04060) vicX 417748..418560 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  LLL8_RS02100 (LLL8_04070) vicK 418730..420172 (-) 1443 WP_010905315.1 cell wall metabolism sensor histidine kinase WalK Regulator
  LLL8_RS02105 (LLL8_04080) yycF 420165..420866 (-) 702 WP_003131580.1 response regulator YycF -
  LLL8_RS02110 (LLL8_04090) tmk 421044..421679 (+) 636 WP_012897230.1 dTMP kinase -
  LLL8_RS02115 (LLL8_04100) - 421812..422672 (+) 861 WP_003131573.1 DNA polymerase III subunit delta' -
  LLL8_RS02120 (LLL8_04110) yaaT 422724..423506 (+) 783 WP_010905316.1 stage 0 sporulation family protein Regulator
  LLL8_RS02125 (LLL8_04120) yabA 423499..423825 (+) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  LLL8_RS02130 (LLL8_04130) rsmI 423825..424700 (+) 876 WP_251900140.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  LLL8_RS02135 (LLL8_04140) - 424777..424968 (-) 192 WP_012897234.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54695.14 Da        Isoelectric Point: 4.5889

>NTDB_id=78509 LLL8_RS02100 WP_010905315.1 418730..420172(-) (vicK) [Lactococcus lactis strain L8]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKITDQYNFYDLLEKEPEITIETHDSGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=78509 LLL8_RS02100 WP_010905315.1 418730..420172(-) (vicK) [Lactococcus lactis strain L8]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCCCACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGTGATAAAATC
CCAAAAGGGACAAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTCGGTGAAGATATTGTTCGCACACAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCACTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTACTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATTC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGGATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTCTC
TATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGTTCTGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGTACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CIG6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442

Multiple sequence alignment