Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   Q3V78_RS05890 Genome accession   NZ_CP130538
Coordinates   1171333..1173114 (+) Length   593 a.a.
NCBI ID   WP_000390515.1    Uniprot ID   -
Organism   Staphylococcus aureus strain SA11-SX     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1166333..1178114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q3V78_RS05870 polX 1166449..1168161 (+) 1713 WP_117197139.1 DNA polymerase/3'-5' exonuclease PolX -
  Q3V78_RS05875 mutS/mutS2 1168171..1170519 (+) 2349 WP_001249271.1 endonuclease MutS2 Machinery gene
  Q3V78_RS05880 trxA 1170695..1171009 (+) 315 WP_001018928.1 thioredoxin -
  Q3V78_RS05885 - 1171072..1171167 (-) 96 WP_001803554.1 hypothetical protein -
  Q3V78_RS05890 uvrC 1171333..1173114 (+) 1782 WP_000390515.1 excinuclease ABC subunit UvrC Machinery gene
  Q3V78_RS05895 - 1173438..1174052 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  Q3V78_RS05900 sdhA 1174104..1175870 (+) 1767 WP_031927766.1 succinate dehydrogenase flavoprotein subunit -
  Q3V78_RS05905 sdhB 1175870..1176685 (+) 816 WP_303262006.1 succinate dehydrogenase iron-sulfur subunit -
  Q3V78_RS05910 racE 1176924..1177724 (+) 801 WP_001039651.1 glutamate racemase -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68657.38 Da        Isoelectric Point: 9.8215

>NTDB_id=784829 Q3V78_RS05890 WP_000390515.1 1171333..1173114(+) (uvrC) [Staphylococcus aureus strain SA11-SX]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLIGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLNKEMI
QSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGSKRKTLLLRSF
GSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=784829 Q3V78_RS05890 WP_000390515.1 1171333..1173114(+) (uvrC) [Staphylococcus aureus strain SA11-SX]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGCTTGCGATCGTATTTTACGGGCGCTCATGATG
CTAAAACAACGAGACTGATTGGAGAAATACGTCGCTTTGAGTTTATTGTCACGTCAAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATTAAACAATATCAACCTAGATACAACATTTTATTAAAAGATGATAAAAGTTATCCATTTATTAAAAT
AACAAAGGAAAAATATCCTAGACTACTAGTGACGAGAACCGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGGGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAATAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCCTTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGTTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGAATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACAATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATCCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGATGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCGGATTTAATTA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAAAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACATTTCATAGACAAACACGTC
AAAAGACAGGCTTGAAATCAATCCTTGATGATATAGATGGTATCGGTAGCAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTCGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.094

98.651

0.563
  uvrC Streptococcus pneumoniae R6

57.094

98.651

0.563
  uvrC Streptococcus pneumoniae D39

57.094

98.651

0.563