Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MTP06_RS16030 Genome accession   NZ_AP025692
Coordinates   3725372..3726031 (-) Length   219 a.a.
NCBI ID   WP_248495333.1    Uniprot ID   -
Organism   Streptomyces sp. PLM4     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3720372..3731031
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MTP06_RS16005 (MTP06_32190) - 3720460..3720900 (-) 441 WP_248496804.1 ATP-binding protein -
  MTP06_RS16010 (MTP06_32200) - 3721189..3722541 (+) 1353 WP_248495329.1 hypothetical protein -
  MTP06_RS16015 (MTP06_32210) - 3722719..3723258 (+) 540 WP_248495330.1 GNAT family N-acetyltransferase -
  MTP06_RS16020 (MTP06_32220) - 3723308..3723850 (+) 543 WP_248495331.1 flavoprotein -
  MTP06_RS16025 (MTP06_32230) - 3723974..3724552 (-) 579 WP_121841309.1 DUF4352 domain-containing protein -
  MTP06_RS16030 (MTP06_32240) vraR 3725372..3726031 (-) 660 WP_248495333.1 response regulator transcription factor Regulator
  MTP06_RS16035 (MTP06_32250) - 3726040..3727323 (-) 1284 WP_248495335.1 sensor histidine kinase -
  MTP06_RS16040 (MTP06_32260) - 3727718..3728278 (+) 561 WP_248495337.1 heme-binding protein -
  MTP06_RS16045 (MTP06_32270) - 3728337..3728957 (+) 621 WP_248495339.1 ankyrin repeat domain-containing protein -
  MTP06_RS16050 (MTP06_32280) - 3728999..3729406 (-) 408 WP_003949595.1 RidA family protein -
  MTP06_RS16055 (MTP06_32290) - 3729578..3729958 (+) 381 WP_248495341.1 helix-turn-helix domain-containing protein -
  MTP06_RS16060 (MTP06_32300) - 3729962..3730654 (-) 693 WP_186780984.1 hypothetical protein -
  MTP06_RS16065 - 3730812..3731012 (-) 201 WP_075986756.1 DUF397 domain-containing protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23559.00 Da        Isoelectric Point: 6.3859

>NTDB_id=78374 MTP06_RS16030 WP_248495333.1 3725372..3726031(-) (vraR) [Streptomyces sp. PLM4]
MPAPTDEPPTPAPVRLLLCDDHAVVRAGLRALLSSAPGIEVVAEAGSGDEALALTTLHHPDLVLMDLQLGEGIDGVETTR
RLTTLPDHPPYVLVLTTYDTDADITRAVEAGATGYLLKAERPEELFTAIRAAASGRTALSPPVAQRVMTHLRNPQPELTP
RERDILRHLTQGLGNREIARALFISEATVKTHLGRIYQKLGVETRAGAVAVGKERRLLG

Nucleotide


Download         Length: 660 bp        

>NTDB_id=78374 MTP06_RS16030 WP_248495333.1 3725372..3726031(-) (vraR) [Streptomyces sp. PLM4]
GTGCCCGCCCCCACCGACGAGCCGCCCACCCCTGCCCCCGTACGCCTCCTCCTCTGCGACGACCACGCCGTGGTCCGCGC
CGGCCTGCGCGCCCTCCTCTCCAGCGCCCCCGGCATCGAGGTCGTGGCCGAAGCAGGCAGCGGCGACGAAGCCCTCGCCC
TGACCACCCTCCACCACCCCGACCTGGTCCTCATGGACCTCCAACTAGGCGAAGGAATCGACGGAGTCGAAACCACCCGC
CGCCTCACCACCCTCCCCGACCACCCCCCGTACGTCCTCGTCCTCACCACCTACGACACCGACGCCGACATCACCCGAGC
CGTCGAAGCCGGCGCCACCGGCTACCTCCTGAAAGCCGAACGCCCCGAAGAACTCTTCACGGCCATCAGGGCTGCGGCCT
CGGGGCGTACGGCGTTGTCCCCGCCTGTGGCGCAGAGGGTGATGACTCACTTGCGGAACCCGCAGCCGGAGCTGACCCCG
AGGGAGCGGGACATTCTGCGGCACTTGACGCAAGGGCTGGGGAACCGGGAGATCGCCAGGGCGTTGTTCATCAGCGAGGC
GACGGTGAAGACCCATCTGGGCCGGATTTACCAGAAGTTGGGGGTGGAGACACGGGCGGGGGCGGTGGCTGTGGGAAAGG
AGCGGCGGTTGTTGGGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-210)

Response regulator receiver domain (Response_reg)

(17-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.559

97.26

0.365
  degU Bacillus subtilis subsp. subtilis str. 168

35.909

100

0.361

Multiple sequence alignment