Detailed information NTG0078366

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: MTP06_RS12470
• Genome accession: NZ_AP025692
• Coordinates: 2880254..2881375 (+)
• Length: 373 a.a.
• NCBI ID: WP_010645237.1
• Uniprot ID: A0A385DDD7
• Organism: Streptomyces sp. PLM4
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2875254..2886375

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MTP06_RS12455 (MTP06_25030)	-	2876003..2877757 (-)	1755	WP_186784029.1	sigma factor-like helix-turn-helix DNA-binding protein	-
MTP06_RS12460 (MTP06_25050)	-	2878036..2878611 (+)	576	WP_003948874.1	dihydrofolate reductase family protein	-
MTP06_RS12465 (MTP06_25060)	radA/sms	2878665..2880083 (+)	1419	WP_003948876.1	DNA repair protein RadA	Machinery gene
MTP06_RS12470 (MTP06_25070)	disA	2880254..2881375 (+)	1122	WP_010645237.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
MTP06_RS12475 (MTP06_25080)	-	2881457..2882269 (-)	813	WP_240679261.1	hypothetical protein	-
MTP06_RS12480 (MTP06_25090)	-	2882625..2883374 (+)	750	WP_008404973.1	phosphatase PAP2 family protein	-
MTP06_RS12485 (MTP06_25100)	-	2883487..2884539 (+)	1053	WP_008404974.1	A/G-specific adenine glycosylase	-
MTP06_RS12490 (MTP06_25110)	-	2884748..2885287 (+)	540	WP_003948881.1	SigE family RNA polymerase sigma factor	-
MTP06_RS12495 (MTP06_25120)	-	2885308..2885976 (+)	669	WP_018895477.1	hypothetical protein	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 40215.10 Da
• Isoelectric Point: 5.1034

>NTDB_id=78366 MTP06_RS12470 WP_010645237.1 2880254..2881375(+) (disA) [Streptomyces sp. PLM4]
MAANDRATAPGKSGGPGADGLMRASLSAVAPGTQLRDGLERILRGNTGGLIVLGWDKTVESMCTGGFVLDVEFSATRLRE
LCKLDGGIVLDKDLTKILRAGVQLVPDPTIPTDETGTRHRTADRVSKQVNFPVVSVSQSMRLIALYVDGQRRVLEDSAAI
LSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVSQRLEMVRRIAAEIAEYVVELGTDGRLLALQLDELIAG
VEPERELVVRDYVPEPTAKRSRTVDEALAELGKLSHTELLELPVVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGAI
IDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1122 bp

>NTDB_id=78366 MTP06_RS12470 WP_010645237.1 2880254..2881375(+) (disA) [Streptomyces sp. PLM4]
GTGGCAGCCAATGACCGGGCAACGGCCCCCGGCAAGTCCGGCGGGCCCGGTGCCGACGGGCTGATGCGTGCCTCGCTGAG
CGCCGTCGCCCCCGGCACCCAGCTGCGGGACGGGCTGGAGCGGATTCTGCGGGGGAACACCGGCGGACTCATCGTGCTCG
GCTGGGACAAGACCGTCGAGTCGATGTGTACCGGCGGCTTCGTGCTGGACGTCGAGTTCTCCGCGACCCGCCTGCGCGAG
CTGTGCAAGCTCGACGGCGGCATCGTCCTCGACAAGGACCTCACCAAGATCCTGCGCGCCGGAGTCCAGCTCGTCCCCGA
CCCGACCATCCCCACCGACGAGACCGGCACCCGGCACCGCACCGCCGACCGCGTCTCCAAGCAGGTCAACTTCCCCGTGG
TCTCGGTCAGCCAGTCGATGCGGCTGATCGCGCTCTACGTGGACGGGCAGCGCCGGGTCCTGGAGGACTCGGCCGCCATC
CTCTCCCGCGCCAACCAGGCCCTCGCGACGCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTGGCCGGCACGCTCTCGGC
GCTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTCACGGCCGTCTCGCAGCGGCTGGAGATGGTCCGCCGGATCGCCG
CCGAGATCGCCGAGTACGTGGTGGAACTGGGCACCGACGGGCGTCTGCTCGCCCTCCAGCTGGACGAGCTGATCGCCGGC
GTCGAGCCCGAACGCGAGCTGGTCGTCCGGGACTACGTGCCGGAACCCACGGCGAAGCGTTCCCGGACGGTGGACGAGGC
GCTGGCGGAGCTGGGCAAGCTCAGCCACACCGAGCTGCTCGAACTGCCCGTGGTGGCGCGGGCGCTCGGCTACACCGGCT
CGCCGGAGGCGCTGGACTCCGCGGTGTCGCCGCGCGGCTTCCGCCTCCTGGCGAAGGTGCCGCGGCTGCCCGGGGCCATC
ATCGACCGGCTGGTGGAGCACTTCGGCGGCCTGCAGAAGCTGCTGGCGGCCAGTGTGGACGACCTCCAGACGGTGGACGG
CGTCGGCGAGGCCCGCGCCCGCAGCGTCCGCGAGGGCCTCTCCCGCCTGGCCGAGTCGTCGATCCTGGAGCGGTACGTCT
GA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (37-150)

• DisA bacterial checkpoint controller linker region (DisA-linker) (154-296)

• Helix-hairpin-helix motif (HHH_2) (323-358)

3D structure

• AlphaFold DB: A0A385DDD7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.532	92.761	0.432