Detailed information NTG0783296

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: MGCS36044_RS00355
• Genome accession: NZ_CP117287
• Coordinates: 55455..56366 (+)
• Length: 303 a.a.
• NCBI ID: WP_003060893.1
• Uniprot ID: A0AAE9U6L1
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGCS36044
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 50455..61366

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGCS36044_RS00330 (MGCS36044_00132)	purE	50956..51444 (+)	489	WP_012766417.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
MGCS36044_RS00335 (MGCS36044_00134)	purK	51431..52504 (+)	1074	WP_003055561.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
MGCS36044_RS00340 (MGCS36044_00136)	-	52514..53770 (+)	1257	WP_003055555.1	DUF4041 domain-containing protein	-
MGCS36044_RS00345 (MGCS36044_00138)	-	53763..53972 (+)	210	WP_014611912.1	hypothetical protein	-
MGCS36044_RS00350 (MGCS36044_00140)	purB	54021..55313 (+)	1293	WP_003056595.1	adenylosuccinate lyase	-
MGCS36044_RS00355 (MGCS36044_00142)	comR	55455..56366 (+)	912	WP_003060893.1	helix-turn-helix domain-containing protein	Regulator
MGCS36044_RS00360 (MGCS36044_00144)	comS	56453..56551 (+)	99	WP_014611913.1	quorum-sensing system DWW-type pheromone	Regulator
MGCS36044_RS00365 (MGCS36044_00146)	ruvB	56585..57583 (+)	999	WP_015057190.1	Holliday junction branch migration DNA helicase RuvB	-
MGCS36044_RS00370 (MGCS36044_00148)	-	57718..58149 (+)	432	WP_003059365.1	low molecular weight protein-tyrosine-phosphatase	-
MGCS36044_RS00375 (MGCS36044_00150)	-	58178..58579 (+)	402	WP_003049089.1	MORN repeat-containing protein	-
MGCS36044_RS00380 (MGCS36044_00152)	-	58576..60351 (+)	1776	WP_003059359.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35995.62 Da
• Isoelectric Point: 4.7392

>NTDB_id=783296 MGCS36044_RS00355 WP_003060893.1 55455..56366(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36044]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEKIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKKTVYNLNE
LLLIDLYLIILVVSNFTNDLFDEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQKEWDKDIHPS

Nucleotide

• Length: 912 bp

>NTDB_id=783296 MGCS36044_RS00355 WP_003060893.1 55455..56366(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36044]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAAAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAAAACGGTTTATAACTTAAATGAA
TTATTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCTAACTTTACAAATGACCTATTTGATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAATACCTGTTATTAGAAGATTTATTTCTATTAAATAATATTCTTTTAT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAGCGAATGCCCATGTATTGCATGTATGAATGGAAATTGTCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAA
AAGAATGGGATAAGGATATTCATCCCTCTTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	83.389	99.34	0.828
comR	Streptococcus pyogenes MGAS8232	55.629	99.67	0.554
comR	Streptococcus mutans UA159	46.154	98.68	0.455
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.575	96.37	0.449
comR	Streptococcus suis P1/7	37.288	97.36	0.363
comR	Streptococcus suis 05ZYH33	37.288	97.36	0.363