Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   MGGS36055_RS03330 Genome accession   NZ_CP117286
Coordinates   603172..604524 (+) Length   450 a.a.
NCBI ID   WP_014612101.1    Uniprot ID   A0AB38Y2E7
Organism   Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 598172..609524
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGGS36055_RS03305 (MGGS36055_01336) - 599239..599886 (-) 648 WP_003057245.1 amino acid ABC transporter permease -
  MGGS36055_RS03310 (MGGS36055_01338) - 599901..600602 (-) 702 WP_015016780.1 amino acid ABC transporter permease -
  MGGS36055_RS03315 (MGGS36055_01340) - 600616..601416 (-) 801 WP_003057243.1 transporter substrate-binding domain-containing protein -
  MGGS36055_RS03320 (MGGS36055_01342) - 601416..602210 (-) 795 WP_003057217.1 amino acid ABC transporter ATP-binding protein -
  MGGS36055_RS03325 (MGGS36055_01344) vicR 602469..603179 (+) 711 WP_012766682.1 response regulator YycF Regulator
  MGGS36055_RS03330 (MGGS36055_01346) vicK 603172..604524 (+) 1353 WP_014612101.1 cell wall metabolism sensor histidine kinase VicK Regulator
  MGGS36055_RS03335 (MGGS36055_01348) vicX 604528..605337 (+) 810 WP_003059746.1 MBL fold metallo-hydrolase Regulator
  MGGS36055_RS03340 (MGGS36055_01350) rnc 606095..606787 (+) 693 WP_003057240.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51476.06 Da        Isoelectric Point: 5.7411

>NTDB_id=783263 MGGS36055_RS03330 WP_014612101.1 603172..604524(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=783263 MGGS36055_RS03330 WP_014612101.1 603172..604524(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055]
ATGACTAGAGATATCATTGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACGCCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACTAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-165)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.188

92

0.673
  micB Streptococcus pneumoniae Cp1015

66.588

94.444

0.629