Detailed information NTG0783243

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: MGGS36055_RS00740
• Genome accession: NZ_CP117286
• Coordinates: 120622..121653 (+)
• Length: 343 a.a.
• NCBI ID: WP_042357807.1
• Uniprot ID: A0AB38Y521
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 115622..126653

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGGS36055_RS00730 (MGGS36055_00294)	-	119299..119664 (+)	366	WP_003055257.1	DUF1033 family protein	-
MGGS36055_RS00735 (MGGS36055_00296)	comGA/cglA	119745..120686 (+)	942	WP_015016543.1	competence type IV pilus ATPase ComGA	Machinery gene
MGGS36055_RS00740 (MGGS36055_00298)	comYB	120622..121653 (+)	1032	WP_042357807.1	competence type IV pilus assembly protein ComGB	Machinery gene
MGGS36055_RS00745 (MGGS36055_00300)	comYC	121655..121981 (+)	327	WP_003055259.1	competence type IV pilus major pilin ComGC	Machinery gene
MGGS36055_RS00750 (MGGS36055_00302)	comGD	121956..122384 (+)	429	WP_041788719.1	competence type IV pilus minor pilin ComGD	-
MGGS36055_RS00755 (MGGS36055_00304)	comGE	122392..122637 (+)	246	WP_003058569.1	competence type IV pilus minor pilin ComGE	-
MGGS36055_RS00760 (MGGS36055_00306)	comGF	122618..123058 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	-
MGGS36055_RS00765 (MGGS36055_00308)	comGG	123087..123410 (+)	324	WP_227985720.1	competence type IV pilus minor pilin ComGG	-
MGGS36055_RS00770 (MGGS36055_00310)	comYH	123473..124426 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
MGGS36055_RS00775 (MGGS36055_00312)	-	124485..125681 (+)	1197	WP_003058485.1	acetate kinase	-
MGGS36055_RS00780 (MGGS36055_00314)	-	125987..126193 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 38983.37 Da
• Isoelectric Point: 9.2055

>NTDB_id=783243 MGGS36055_RS00740 WP_042357807.1 120622..121653(+) (comYB) [Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055]
MTFLQRDISVRSKQGLKKLSSKEQYKLIQLLANLLLTGFNLAEIIAFLTKSHLIPEPYVLRMEEALLKGRGLADMLAGIG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVMILGLRHYVMPQLEAQNQLTIFLTH
FPAIFFGIILFIGVLLGGIWLHWRSQSRLKLFTHFSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMTMEKSL
FMQELAEDIRVSLLAGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWTQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide

• Length: 1032 bp

>NTDB_id=783243 MGGS36055_RS00740 WP_042357807.1 120622..121653(+) (comYB) [Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055]
ATGACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAAGGAACAATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACTTGGCTGAGATAATAGCTTTCTTAACAAAAAGTCATTTGA
TTCCCGAGCCCTATGTTCTCCGCATGGAAGAAGCACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGATAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGAAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTCCTGGTATTTCTTT
TTGTGATGATATTAGGGTTAAGGCATTATGTTATGCCTCAATTAGAAGCTCAAAATCAGCTTACTATTTTTCTGACTCAT
TTTCCAGCTATTTTCTTTGGTATTATCCTTTTTATAGGTGTGCTGTTAGGGGGAATTTGGCTGCATTGGCGATCGCAAAG
TCGCCTCAAGCTTTTTACTCACTTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGACAGGGACTTGAATTACCAGTCATTCTGGATATTATGACCATGGAGAAATCTTTA
TTCATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTATTGGCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTTAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAGTTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGACTCAGTTTTTCAGCCAACTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (28-146)

• Type II secretion system (T2SS), protein F (T2SSF) (214-334)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	53.392	98.834	0.528
comYB	Streptococcus mutans UA159	53.392	98.834	0.528
comYB	Streptococcus gordonii str. Challis substr. CH1	48.673	98.834	0.481
comGB/cglB	Streptococcus mitis NCTC 12261	45.97	97.668	0.449
comGB/cglB	Streptococcus mitis SK321	45.345	97.085	0.44
comGB/cglB	Streptococcus pneumoniae Rx1	43.844	97.085	0.426
comGB/cglB	Streptococcus pneumoniae D39	43.844	97.085	0.426
comGB/cglB	Streptococcus pneumoniae R6	43.844	97.085	0.426
comGB/cglB	Streptococcus pneumoniae TIGR4	43.844	97.085	0.426
comGB	Lactococcus lactis subsp. cremoris KW2	42.773	98.834	0.423