Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   MGCS36083_RS08475 Genome accession   NZ_CP117285
Coordinates   1696547..1697872 (-) Length   441 a.a.
NCBI ID   WP_015017291.1    Uniprot ID   A0A9X8T4I6
Organism   Streptococcus dysgalactiae subsp. equisimilis strain MGCS36083     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1691547..1702872
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGCS36083_RS08460 (MGCS36083_03440) - 1694184..1695152 (-) 969 WP_022554204.1 IS30 family transposase -
  MGCS36083_RS08465 (MGCS36083_03442) hpf 1695282..1695830 (-) 549 WP_084916484.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  MGCS36083_RS10970 (MGCS36083_03444) - 1695910..1696575 (-) 666 WP_012767419.1 ComF family protein -
  MGCS36083_RS08475 (MGCS36083_03446) comFA/cflA 1696547..1697872 (-) 1326 WP_015017291.1 DEAD/DEAH box helicase Machinery gene
  MGCS36083_RS08480 (MGCS36083_03448) - 1697928..1698566 (+) 639 WP_084916482.1 YigZ family protein -
  MGCS36083_RS08485 (MGCS36083_03450) cysK 1698670..1699605 (+) 936 WP_084916480.1 cysteine synthase A -
  MGCS36083_RS08490 (MGCS36083_03452) - 1699758..1700117 (-) 360 WP_003056775.1 S1 RNA-binding domain-containing protein -
  MGCS36083_RS08495 (MGCS36083_03454) - 1700117..1701517 (-) 1401 WP_042357970.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  MGCS36083_RS08500 (MGCS36083_03456) - 1701554..1702195 (-) 642 WP_014612503.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49283.45 Da        Isoelectric Point: 9.7069

>NTDB_id=783221 MGCS36083_RS08475 WP_015017291.1 1696547..1697872(-) (comFA/cflA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36083]
MEGIENSYGRLFLKHQLPKEVNHLAKTLESIVAIKGKVTCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPP
HPFPIANYLQWKGILTPYQESISNQLVKNVHAKKPTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANR
LKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYAAQQAAKEGASSIVLTATST
KELEEQVKSGELEKLTLARRFHDNPLILPKFIRSFGLLKKIHCQKLPRALVKSISQQRKTGCPLLIFLPIIAMAELVTEL
LKLAFPEEQIACVSSQSADRVKDIDAFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIER
PTGKVYFFHDGISQAMRNARKEIKEMNQKGYLNDMPPMSTI

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=783221 MGCS36083_RS08475 WP_015017291.1 1696547..1697872(-) (comFA/cflA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36083]
ATGGAAGGTATCGAAAACAGTTACGGTCGTTTATTTTTAAAACATCAATTGCCAAAAGAAGTAAATCATCTGGCAAAGAC
CTTGGAAAGTATAGTAGCCATAAAAGGTAAAGTCACTTGTCAACGCTGTCATTATCAGATAACCGCAGAAGCGAGATTAC
CAAGTGGCACTTACTACTGCCGCTTCTGTCTCGTTTTTGGCCGAAATCAAGCTGATAGGCCTCTTTATTATATACCTCCA
CATCCTTTTCCTATAGCCAATTATCTTCAATGGAAGGGGATATTAACGCCCTACCAAGAAAGTATTTCAAACCAATTAGT
CAAGAATGTTCATGCTAAAAAACCTACTTTAGTGCATGCTGTTACCGGAGCCGGCAAGACAGAGATGATTTATGGAGCCA
TAGCAGCAGTTGTTAATGCTGGAGGTTGGGTTTGTTTAGCCAGCCCAAGGGTCGATGTTTGTATAGAACTTGCTAATCGC
TTAAAAGCTGCTTTTTCTTGCCGGGTTACTCTTTTACATGCTGACTCAGAAGCTTATCAAAGAAGTCCTATTATAGTAGC
TACTACCCATCAATTACTGACCTTTTATAAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCTTTTCCTTTTGTCA
ATAATCATCAACTACAATATGCAGCGCAGCAAGCCGCTAAAGAAGGCGCTAGTAGTATCGTATTGACCGCGACATCGACC
AAAGAACTGGAAGAGCAGGTCAAAAGTGGGGAACTAGAGAAGTTGACATTAGCTAGACGATTCCACGATAATCCTTTAAT
TCTTCCGAAATTTATCAGGAGTTTTGGTCTATTAAAAAAAATTCACTGTCAAAAACTTCCTCGAGCTCTTGTTAAATCTA
TCAGTCAACAAAGGAAAACAGGATGTCCACTGCTAATTTTTCTTCCTATTATTGCCATGGCAGAATTAGTTACTGAATTA
TTAAAGTTAGCTTTTCCAGAGGAACAAATTGCCTGTGTCTCTAGCCAATCAGCTGACAGAGTTAAAGACATTGATGCCTT
TCGTCAAGGAAAGAAAGGTATTTTGGTGACCACCACAATATTGGAAAGGGGTGTTACTTTCCCAGGCGTGGATGTCTTTG
TGCTTATGGCACAGCATCGAGGATACAGTTCTCAAAGCTTGGTTCAAATCGCAGGTCGTGTGGGGAGATCTATCGAAAGG
CCAACAGGGAAGGTGTATTTCTTTCACGATGGGATTAGCCAAGCAATGCGCAATGCAAGAAAAGAAATTAAAGAAATGAA
TCAGAAAGGTTATTTGAATGATATGCCTCCTATGTCAACAATTTAG

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-396)

DEAD/DEAH box helicase (DEAD)

(99-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.302

96.145

0.512
  comFA/cflA Streptococcus pneumoniae D39

53.302

96.145

0.512
  comFA/cflA Streptococcus pneumoniae R6

53.302

96.145

0.512
  comFA/cflA Streptococcus pneumoniae TIGR4

53.302

96.145

0.512
  comFA/cflA Streptococcus mitis NCTC 12261

51.852

97.959

0.508
  comFA/cflA Streptococcus mitis SK321

52.214

97.279

0.508
  comFA Lactococcus lactis subsp. cremoris KW2

46.465

89.796

0.417
  comFA Latilactobacillus sakei subsp. sakei 23K

37.587

97.732

0.367