Detailed information
Bioinformatically predicted
Overview
| Name | comK/comK1 | Type | Regulator |
| Locus tag | PQQ26_RS04595 | Genome accession | NZ_CP117230 |
| Coordinates | 965154..965723 (-) | Length | 189 a.a. |
| NCBI ID | WP_000287265.1 | Uniprot ID | A0A7U7EXU5 |
| Organism | Staphylococcus aureus strain ATCC 25923 | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 965825..1002502 | 965154..965723 | flank | 102 |
Gene organization within MGE regions
Location: 965154..1002502
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PQQ26_RS04595 (PQQ26_04595) | comK/comK1 | 965154..965723 (-) | 570 | WP_000287265.1 | competence protein ComK | Regulator |
| PQQ26_RS04600 (PQQ26_04600) | - | 965933..966151 (+) | 219 | WP_000876825.1 | IDEAL domain-containing protein | - |
| PQQ26_RS04605 (PQQ26_04605) | - | 966232..967218 (-) | 987 | WP_000668822.1 | lipoate--protein ligase | - |
| PQQ26_RS04610 (PQQ26_04610) | - | 967417..967593 (+) | 177 | WP_000214898.1 | YkvS family protein | - |
| PQQ26_RS04615 (PQQ26_04615) | - | 967608..968210 (+) | 603 | WP_001033867.1 | CPBP family glutamic-type intramembrane protease | - |
| PQQ26_RS04620 (PQQ26_04620) | - | 969127..969228 (+) | 102 | WP_001790623.1 | hypothetical protein | - |
| PQQ26_RS04625 (PQQ26_04625) | - | 969250..969510 (+) | 261 | WP_223200471.1 | lactococcin 972 family bacteriocin | - |
| PQQ26_RS04630 (PQQ26_04630) | - | 969554..971518 (+) | 1965 | WP_000870820.1 | bacteriocin-associated integral membrane family protein | - |
| PQQ26_RS04635 (PQQ26_04635) | - | 971521..971841 (+) | 321 | WP_000873929.1 | YxeA family protein | - |
| PQQ26_RS04640 (PQQ26_04640) | - | 971838..972479 (+) | 642 | WP_000571183.1 | ABC transporter ATP-binding protein | - |
| PQQ26_RS04645 (PQQ26_04645) | - | 972567..972857 (-) | 291 | WP_001791476.1 | hypothetical protein | - |
| PQQ26_RS04650 (PQQ26_04650) | - | 973198..973485 (+) | 288 | WP_000410718.1 | hypothetical protein | - |
| PQQ26_RS04655 (PQQ26_04655) | - | 973491..974972 (+) | 1482 | WP_000719183.1 | glycosyltransferase | - |
| PQQ26_RS04660 (PQQ26_04660) | - | 975062..975418 (-) | 357 | WP_000766009.1 | DoxX family protein | - |
| PQQ26_RS04665 (PQQ26_04665) | - | 975909..976631 (+) | 723 | Protein_909 | ABC transporter substrate-binding protein | - |
| PQQ26_RS04670 (PQQ26_04670) | - | 976685..976969 (+) | 285 | WP_000134551.1 | hypothetical protein | - |
| PQQ26_RS04675 (PQQ26_04675) | - | 977120..977440 (+) | 321 | WP_000805733.1 | DUF961 family protein | - |
| PQQ26_RS04680 (PQQ26_04680) | - | 977454..977756 (+) | 303 | WP_000386891.1 | hypothetical protein | - |
| PQQ26_RS04685 (PQQ26_04685) | - | 977931..979022 (+) | 1092 | WP_000172936.1 | replication initiation factor domain-containing protein | - |
| PQQ26_RS04690 (PQQ26_04690) | - | 979083..980150 (+) | 1068 | WP_000692013.1 | conjugal transfer protein | - |
| PQQ26_RS04695 (PQQ26_04695) | - | 980155..980415 (+) | 261 | WP_000015640.1 | TcpD family membrane protein | - |
| PQQ26_RS04700 (PQQ26_04700) | - | 980427..980810 (+) | 384 | WP_000358144.1 | TcpE family conjugal transfer membrane protein | - |
| PQQ26_RS04705 (PQQ26_04705) | - | 980845..983340 (+) | 2496 | WP_001049264.1 | ATP-binding protein | - |
| PQQ26_RS04710 (PQQ26_04710) | - | 983394..984752 (+) | 1359 | WP_001251204.1 | FtsK/SpoIIIE domain-containing protein | - |
| PQQ26_RS04715 (PQQ26_04715) | - | 984757..986604 (+) | 1848 | WP_000681144.1 | membrane protein | - |
| PQQ26_RS04720 (PQQ26_04720) | - | 986594..987640 (+) | 1047 | WP_000247481.1 | CHAP domain-containing protein | - |
| PQQ26_RS04725 (PQQ26_04725) | - | 987647..988237 (+) | 591 | WP_000810442.1 | hypothetical protein | - |
| PQQ26_RS04730 (PQQ26_04730) | - | 988293..988634 (+) | 342 | WP_001255377.1 | cystatin-like fold lipoprotein | - |
| PQQ26_RS04735 (PQQ26_04735) | - | 988743..989246 (+) | 504 | WP_000746374.1 | transposase | - |
| PQQ26_RS04740 (PQQ26_04740) | - | 989275..989763 (+) | 489 | WP_232471205.1 | IS30 family transposase | - |
| PQQ26_RS04745 (PQQ26_04745) | - | 989983..990222 (+) | 240 | Protein_925 | ABC transporter substrate-binding protein | - |
| PQQ26_RS04750 (PQQ26_04750) | - | 990269..990400 (-) | 132 | WP_001794249.1 | SAR1012 family small protein | - |
| PQQ26_RS04755 (PQQ26_04755) | - | 990464..990679 (-) | 216 | WP_000867359.1 | NINE protein | - |
| PQQ26_RS04760 (PQQ26_04760) | - | 990844..991395 (+) | 552 | WP_000620943.1 | GNAT family N-acetyltransferase | - |
| PQQ26_RS04765 (PQQ26_04765) | - | 991447..992385 (-) | 939 | WP_000070966.1 | 1,4-dihydroxy-2-naphthoate polyprenyltransferase | - |
| PQQ26_RS04770 (PQQ26_04770) | - | 992536..992613 (+) | 78 | WP_072357920.1 | hypothetical protein | - |
| PQQ26_RS04775 (PQQ26_04775) | - | 992606..993928 (+) | 1323 | WP_223200472.1 | isochorismate synthase MenF | - |
| PQQ26_RS04780 (PQQ26_04780) | menD | 993915..995588 (+) | 1674 | WP_000526678.1 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | - |
| PQQ26_RS04785 (PQQ26_04785) | menH | 995575..996378 (+) | 804 | WP_000150205.1 | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | - |
| PQQ26_RS04790 (PQQ26_04790) | menB | 996371..997192 (+) | 822 | WP_000184947.1 | 1,4-dihydroxy-2-naphthoyl-CoA synthase | - |
| PQQ26_RS04795 (PQQ26_04795) | sspC | 997428..997757 (-) | 330 | WP_000284455.1 | staphostatin B | - |
| PQQ26_RS04800 (PQQ26_04800) | sspB | 997795..998976 (-) | 1182 | WP_001088793.1 | cysteine protease staphopain B | - |
| PQQ26_RS04805 (PQQ26_04805) | sspA | 999058..1000131 (-) | 1074 | WP_000676568.1 | Glu-specific serine endopeptidase SspA | - |
| PQQ26_RS04810 (PQQ26_04810) | - | 1000659..1001813 (-) | 1155 | WP_000777562.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
Sequence
Protein
Download Length: 189 a.a. Molecular weight: 22601.83 Da Isoelectric Point: 9.6091
>NTDB_id=782944 PQQ26_RS04595 WP_000287265.1 965154..965723(-) (comK/comK1) [Staphylococcus aureus strain ATCC 25923]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK
Nucleotide
Download Length: 570 bp
>NTDB_id=782944 PQQ26_RS04595 WP_000287265.1 965154..965723(-) (comK/comK1) [Staphylococcus aureus strain ATCC 25923]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
TGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCACCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
TGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCACCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comK/comK1 | Staphylococcus aureus MW2 |
100 |
100 |
1 |
| comK/comK1 | Staphylococcus aureus N315 |
100 |
100 |
1 |