Detailed information NTG0782633

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: PO767_RS18060
• Genome accession: NZ_CP117182
• Coordinates: 3625148..3626311 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain Lwp6
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3620148..3631311

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PO767_RS18030	-	3620413..3620832 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
PO767_RS18035	comFC	3620906..3621595 (-)	690	WP_197538213.1	ComF family protein	Machinery gene
PO767_RS18040	-	3621601..3621885 (-)	285	WP_022553866.1	competence protein ComFB	-
PO767_RS18045	comFA	3621943..3623328 (-)	1386	WP_022553867.1	DEAD/DEAH box helicase	Machinery gene
PO767_RS18050	-	3623436..3624284 (-)	849	WP_003151387.1	DegV family protein	-
PO767_RS18055	degU	3624382..3625071 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
PO767_RS18060	degS	3625148..3626311 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
PO767_RS18065	-	3626534..3627181 (+)	648	WP_007407485.1	YigZ family protein	-
PO767_RS18070	-	3627186..3628400 (+)	1215	WP_022553868.1	LCP family protein	-
PO767_RS18075	-	3628500..3629576 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
PO767_RS18080	-	3629708..3630904 (-)	1197	WP_022553869.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=782633 PO767_RS18060 WP_007407484.1 3625148..3626311(-) (degS) [Bacillus velezensis strain Lwp6]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=782633 PO767_RS18060 WP_007407484.1 3625148..3626311(-) (degS) [Bacillus velezensis strain Lwp6]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951